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Low-Volume Interval Training and Resistance Exercise in Individual With Stroke

NCT ID: NCT04623060

Last Updated: 2020-11-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-11-01

Study Completion Date

2021-08-31

Brief Summary

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To examine the feasibility of Low-Volume Interval Training (LV-ITT) and Resistance Exercise (RE) on walking performance (walking endurance, gait speed, functional balance), lower limb muscle strength and quality of life among individuals with post-stroke.

Detailed Description

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Prescribing aerobic and resistance training in concurrence is proposed as an optimum strategy to target cardiovascular as well as musculoskeletal functions in individuals with post-stroke. Lower limb's resistance training alone in chronic stroke produces a large effect on muscle strength. However, it has shown uncertainty results on walking performance. Therefore, it is suggested that to prescribe mix training (treadmill training and strength training) in order to improve muscle strength, gait performance and quality of life in stroke survivors. Previous studies have shown the effect of mixed training on walking performance and endurance in other populations such as multiple sclerosis and coronary artery disease. However, there is a lack of study that conducted mixed training among chronic post-stroke. Therefore, the feasibility study on the effectiveness of combining LV-ITT and RE in post-stroke should be conducted.

Conditions

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Stroke

Keywords

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Low-Volume Interval Training Resistance Training

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Intervention

3 sessions/week for 6 weeks

Group Type EXPERIMENTAL

Combination of Low-volume interval treadmill training and Resistance Training

Intervention Type OTHER

Low-volume interval training (LV-ITT) protocols included a 5 min warm-up (30%-50%VO2peak) up to 20min of LV-ITT and a 5 min cooling down (30%-50% VO2peak). The LV-ITT will repeat 60s bursts of fast treadmill walking at maximum tolerate speed (0% incline), alternate with pre-specified recovery periods about 4 minutes according to protocol. Each time the participants completed a burst successfully, treadmill speed will be increased by 0.1 mph for the next burst. The recovery periods will be 4 minutes. The intervention will be conducted for about 30 minutes.

Resistance training will be conducted by using a horizontal leg press machine. They are encouraged to focus on an explosive concentric movement and a controlled eccentric movement such that the time on each phase was in the ratio 1:2.

Interventions

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Combination of Low-volume interval treadmill training and Resistance Training

Low-volume interval training (LV-ITT) protocols included a 5 min warm-up (30%-50%VO2peak) up to 20min of LV-ITT and a 5 min cooling down (30%-50% VO2peak). The LV-ITT will repeat 60s bursts of fast treadmill walking at maximum tolerate speed (0% incline), alternate with pre-specified recovery periods about 4 minutes according to protocol. Each time the participants completed a burst successfully, treadmill speed will be increased by 0.1 mph for the next burst. The recovery periods will be 4 minutes. The intervention will be conducted for about 30 minutes.

Resistance training will be conducted by using a horizontal leg press machine. They are encouraged to focus on an explosive concentric movement and a controlled eccentric movement such that the time on each phase was in the ratio 1:2.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age range between 45-65 years' old
* At least 3-months post-stroke
* Gait speed ≤1.0 m·s -¹ measured by the 10 m walk test.
* Able to walk 10 m overground with assistive devices as needed and no physical assistance.
* Able to walk for 3 min on the treadmill at ≥0.17 m·s -¹ (0.4 mph) with no aerobic exercise contraindications.
* Modified Rankin Score (mRS) of \<4 at the screening
* American Heart Association class B (2), allowing for aerobic capacity \<6 metabolic equivalent (MET)

Exclusion Criteria

* Significant resting ECG abnormalities
* Hospitalization for cardiac or pulmonary disease within 3 months
* Using Pacemaker
* Aphasia
* Significant musculotendinous or bony restrictions of the affected limb, or any serious chronic disease independently causing disability or profound atrophy of the affected limb that will comprise further indications to participation significant.
Minimum Eligible Age

45 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universiti Teknologi Mara

OTHER

Sponsor Role lead

Responsible Party

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Mohd Haidzir Abd Manaf

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mohd Haidzir Abd Manaf, PhD

Role: PRINCIPAL_INVESTIGATOR

Universiti Teknologi Mara

Locations

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Hospital Selayang

Batu Caves, Selangor, Malaysia

Site Status RECRUITING

Countries

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Malaysia

Central Contacts

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Nur Ainna Adanan, BSc

Role: CONTACT

Phone: 60129471427

Email: [email protected]

Facility Contacts

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Nur Ainna Adanan, BSc

Role: primary

Other Identifiers

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REC/401/19

Identifier Type: -

Identifier Source: org_study_id