The Impact of the Implementation of BIS on the Incidence of Postoperative Delirium

NCT ID: NCT04736303

Last Updated: 2022-08-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

1400 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-12-01

Study Completion Date

2023-04-01

Brief Summary

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This study will investigate the incidence of postoperative POD in patients undergoing non cardiac surgery under general anesthesia with and without the implementation of the BIS monitoring.T

Detailed Description

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This study will compare the incidence of POD after elective non cardiac surgery conducted under general anesthesia before and after the implementation of BIS monitoring in our University Hospital.

The POD will be evaluated with the CAM and Nu-DESC tools, which have been adapted for the greek population.

Conditions

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Postoperative Delirium

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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POD without BIS

Assessing the incidence of POD in patients under general anethesia for elective non cardiac surgery, with CAM and Nu-DESC tools.

Group Type NO_INTERVENTION

No interventions assigned to this group

POD with BIS

Assessing the incidence of POD in patients under general anethesia for elective non cardiac surgery with the implementation of BIS monitoring, with CAM and Nu-DESC tools.

Group Type ACTIVE_COMPARATOR

BIS

Intervention Type DEVICE

The implementation of BIS monitoring

Interventions

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BIS

The implementation of BIS monitoring

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. adult patients over 60 years of age
2. an American Society of Anesthesiologists (ASA) physical status I to III
3. undergoing elective non cardiac surgery under general anaesthesia
4. native speakers of the Greek language
5. eligible to leave the post-anaesthesia care unit
6. an expected in-hospital stay at least 24 hours following surgery

Exclusion Criteria

1. refused to participate or sign the informed consent form
2. surgery or anaesthesia within the last 30 day
3. any prior or current history involving an affliction of the central nervous system
4. severe hearing or visual impairment
5. psychiatric disorders
6. a score less than 5 according the Geriatric Depression Scale (GDS-15)
7. a score less than 4 for females and less than 2 for males according to the Lawton-Brody Instrumental Activities of Daily Living Scale (I.A.D.L.)
8. alcohol consumption less than 35 units/week
9. drug dependence
10. previous neuropsychological testing
11. haemodynamical instability
12. peri-procedural desaturation (one or more events of SpO2\<80% for more than 2 minutes)
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Thessaly

OTHER

Sponsor Role lead

Responsible Party

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Elena Arnaoutoglou

Professor of Anesthesiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Eleni Arnaoutoglou, MD, PhD

Role: STUDY_CHAIR

University of Thessaly

Maria Ntalouka, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University Hospital of Larissa

Locations

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Univeristy of Thessaly

Larissa, Thessaly, Greece

Site Status RECRUITING

Countries

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Greece

Central Contacts

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Eleni Arnaoutoglou, MD, PhD

Role: CONTACT

+306974301352

Maria Ntalouka, MD, PhD

Role: CONTACT

+306973688099

Facility Contacts

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Eleni Arnaoutoglou, MD, PhD

Role: primary

2413501370

Maria Ntalouka, MD

Role: backup

+306973688099

Other Identifiers

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POD and BIS

Identifier Type: -

Identifier Source: org_study_id

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