Impact of Previous Treatment of HCV Patients by DAADs on Covid-19 Disease Frequency and Severity

NCT ID: NCT04729153

Last Updated: 2021-02-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-02-28

Study Completion Date

2022-03-31

Brief Summary

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Evaluate effect of DAADs on covid-19 disease.

Detailed Description

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If Chronic HCV patients who already received DAADs are protected against covid 19 and considered to be immune or not And if DAADS can be used in ttt of covid 19

Conditions

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Covid19

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Chronic HCV patients previously treated by DAADs.

DAAD Compound

Intervention Type DRUG

Sofosbuvir , Daclatasvir and ribavirin

Chronic HCV patients not treated by DAADs yet.

No interventions assigned to this group

Interventions

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DAAD Compound

Sofosbuvir , Daclatasvir and ribavirin

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. HCV patient with or without LC.
2. \>18 years old.
3. Received DAADs at 2019.

Exclusion Criteria

1. Combined HCV and HIV infected patients.
2. Combined HCV and HBV infected patients.
3. \< 18 years old.
4. Pregnant or breast-feeding patients.
5. Patients with autoimmune disease.
6. Patients with multiorgan failure, active cancer, renal insufficiency.
7. Patients received immunosuppressive drugs.
8. Immune compromised patients.
9. Previous confirmed diagnosis of SARS-CoV-2 before starting DAAs.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Eman Adel Zareh

Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Eman Adel

Role: CONTACT

01096883754

Nahed Ahmed

Role: CONTACT

0 100 361 1626

Other Identifiers

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DAADs and covid-19

Identifier Type: -

Identifier Source: org_study_id

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