Impact of Vitamin D Level and Supplement on SLE Patients During COVID-19 Pandemic

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

38 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-01

Study Completion Date

2020-12-30

Brief Summary

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Aim of the work Impact of serum vit D level in SLE patients with COVID-19 disease on severity of infection, duration of COVID-19 disease course, fatigue development as a complication for both SLE and COVID-19 and assess impact of prior chloroquine on COVID-19 disease outcomes Patients and methods 38 SLE patients previously diagnosed and on different lines of lupus management. Participants were presented to chest outpatient clinic and emergency hospital, Mansoura University with manifestation suggesting COVID-19 infection. Serum vit D was measured in serum by ELISA.

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Detailed Description

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Primary objective: assess the impact of serum vit D level in SLE patients with COVID-19 disease on severity of infection and pandemic treatment outcome.

Secondary objectives:

* Effect of serum vit D level in SLE patients on duration of COVID-19 disease course and fatigue development as a complication for both SLE and COVID-19
* Impact of prior chloroquine on COVID-19 disease outcomes
* Correlation of serum vit D level with different laboratory investigations at time of COVID-19 outbreak

Conditions

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Covid19

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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SLE patients

SLE patients were presented to chest outpatient clinic and emergency hospital, Mansoura University with manifestation suggesting COVID-19 infection. Vit D was measured in serum by ELISA. Vit D was added to anti COVID-19.

Vitamin D

Intervention Type DRUG

Impact of serum vit D level in SLE patients with COVID-19 disease on severity of infection, duration of COVID-19 disease course, fatigue development as a complication for both SLE and COVID-19 and assess impact of prior chloroquine on COVID-19 disease outcomes

ELISA

Intervention Type DIAGNOSTIC_TEST

Measure vitamin D level

Interventions

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Vitamin D

Impact of serum vit D level in SLE patients with COVID-19 disease on severity of infection, duration of COVID-19 disease course, fatigue development as a complication for both SLE and COVID-19 and assess impact of prior chloroquine on COVID-19 disease outcomes

Intervention Type DRUG

ELISA

Measure vitamin D level

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Serum Vitamin D level

Eligibility Criteria

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Inclusion Criteria

* \- SLE patients previously diagnosed
* Patients are not suffering from malignancies.
* Patients have no organ failure nor uncontrolled medical illness.
* Recent COVID-19 infection