Surgical Management of Giant Hepatic Hemangioma

NCT ID: NCT04709718

Last Updated: 2021-01-14

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 12 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2008-01-01
• Study Completion Date: 2020-01-02

Brief Summary

Hepatic hemangiomas are the commonest benign mesenchymal lesions of the liver. Most of these lesions are asymptomatic. Giant hepatic hemangiomas (GHH) (> 10 cm) are often symptomatic and require surgical intervention. This study aimed to describe the clinical findings, risk factors, diagnostic approach and management of GHH.

Detailed Description

Hepatic hemangiomas are the most common benign tumors of the liver with the incidence of 0.4 to 20% . They are most often discovered incidentally on imaging studies. Typical hemangiomas usually do not increase in size over time and therefore are unlikely to cause symptoms. Giant hepatic hemangiomas (GHH) are defined as hemangiomas larger than 5 cm . They are usually responsible for overt clinical symptoms and complications consisting, most often, of upper abdominal pain, hemorrhage, biliary compression, or a consumptive coagulopathy that may require prompt surgical intervention or other treatments . Management of liver hemangiomas ranges from close observation to surgery depending upon the site, size and symptoms .

It is widely accepted that intervention is indicated only for symptomatic hemangiomas. Surgical resection is indicated in patients with abdominal complaints or complications, or when diagnosis remains inconclusive. The ideal surgical treatment for GHH is still controversial. Enucleation is the preferred surgical method based on the existing literature. In this study, we report our 17-year experience of clinical management of GHH.

Conditions

Liver Angioma

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Study Groups

churgery of geant liver hemangioma

hepatectomy

Intervention Type: PROCEDURE

liver resection taking over the liver hemangioma

Interventions

hepatectomy

liver resection taking over the liver hemangioma

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Radiological diagnosis of geant liver hamangioma.

Exclusion Criteria

• Radiological diagnosis of liver hemangioma less than 10cm.

• Minimum Eligible Age: 15 Years
• Maximum Eligible Age: 90 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Sahloul Hospital of Sousse

OTHER

Sponsor Role: collaborator

Université de Sousse

OTHER

Sponsor Role: lead

Responsible Party

ammar houssem

clinical professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

waad farhat, doctor

Role: STUDY_DIRECTOR

university of sousse

Other Identifiers

U23464

Identifier Type: -

Identifier Source: org_study_id