Portal Hypertension and Liver Resection in Patients With Hepatocellular Carcinoma
NCT ID: NCT02145013
Last Updated: 2018-02-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
200 participants
OBSERVATIONAL
2013-11-30
2018-05-30
Brief Summary
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However, other guideline treatment, especially from eastern countries demonstrated that surgical resection is safe and feasible and provides better survival than the treatment recommended by the BCLC system for patients with similar stage.
The primary goal of this study is to assess the impact of HVPG on short and long-term outcomes in HCC patients who undergo liver resection.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Portal hypertension
Hepatectomy
Liver resection
Hepatectomy by either open, laparoscopic or robotic procedures
No portal hypertension
Hepatectomy
Liver resection
Hepatectomy by either open, laparoscopic or robotic procedures
Interventions
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Liver resection
Hepatectomy by either open, laparoscopic or robotic procedures
Eligibility Criteria
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Inclusion Criteria
ALL
No
Sponsors
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Henri Mondor University Hospital
OTHER
Responsible Party
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Chetana LIM
MD
Principal Investigators
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Daniel Azoulay, MD PhD
Role: PRINCIPAL_INVESTIGATOR
Henri Mondor
Locations
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Henri Mondor University Hospital
Créteil, , France
Countries
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References
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Ishizawa T, Hasegawa K, Aoki T, Takahashi M, Inoue Y, Sano K, Imamura H, Sugawara Y, Kokudo N, Makuuchi M. Neither multiple tumors nor portal hypertension are surgical contraindications for hepatocellular carcinoma. Gastroenterology. 2008 Jun;134(7):1908-16. doi: 10.1053/j.gastro.2008.02.091. Epub 2008 Mar 8.
Lim C, Salloum C, Chalaye J, Lahat E, Costentin CE, Osseis M, Itti E, Feray C, Azoulay D. 18F-FDG PET/CT predicts microvascular invasion and early recurrence after liver resection for hepatocellular carcinoma: A prospective observational study. HPB (Oxford). 2019 Jun;21(6):739-747. doi: 10.1016/j.hpb.2018.10.007. Epub 2018 Nov 3.
Lim C, Osseis M, Lahat E, Doussot A, Sotirov D, Hemery F, Lanteri-Minet M, Feray C, Salloum C, Azoulay D. Safety of laparoscopic hepatectomy in patients with hepatocellular carcinoma and portal hypertension: interim analysis of an open prospective study. Surg Endosc. 2019 Mar;33(3):811-820. doi: 10.1007/s00464-018-6347-1. Epub 2018 Jul 12.
Lim C, Salloum C, Osseis M, Lahat E, Gomez-Gavara C, Compagnon P, Luciani A, Feray C, Azoulay D. Short-term outcomes following hepatectomy for hepatocellular carcinoma within and beyond the BCLC guidelines: A prospective study. HPB (Oxford). 2018 Mar;20(3):222-230. doi: 10.1016/j.hpb.2017.08.027. Epub 2017 Sep 19.
Other Identifiers
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LIM Chetana
Identifier Type: -
Identifier Source: org_study_id
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