Radiofrequency-assisted Hepatectomy on the Outcomes of HCC Patients With Cirrhosis
NCT ID: NCT01992978
Last Updated: 2015-11-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
200 participants
INTERVENTIONAL
2013-11-30
2018-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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radiofrequency-assisted resection group（RF-R)
Radiofrequency-assisted resection: separating the tumor from liver by using the probe of radiofrequency to block the arterial and vessels before parenchymal transection.
Radiofrequency-assisted Hepatectomy
Radiofrequency-assisted resection: separating the tumor from liver by using the probe of radiofrequency to block the arterial and vessels before parenchymal transection.
conventional liver resection group（CLR-R）
Conventional liver resection group: hepatectomy only without RF assisted during parenchymal transection.Separating and dissecting the tumor with the routine clamp-crushing technical.
Conventional Hepatectomy
Hepatectomy was conducted without RF assisted during parenchymal transection. Separating and dissecting the tumor with the routine clamp-crushing technical.
Interventions
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Radiofrequency-assisted Hepatectomy
Radiofrequency-assisted resection: separating the tumor from liver by using the probe of radiofrequency to block the arterial and vessels before parenchymal transection.
Conventional Hepatectomy
Hepatectomy was conducted without RF assisted during parenchymal transection. Separating and dissecting the tumor with the routine clamp-crushing technical.
Eligibility Criteria
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Inclusion Criteria
* Clinical diagnosis of resectable HCC.
* Preoperative liver function test showed Child-Pugh Class A or B.
* Indocyanine green retention at 15 minutes (ICG-15) of \<30%.
* Acceptable clotting profile :platelet count \> 50 x 109/L and a prolonged prothrombin time of \< 5 seconds.
* Enough relative residual liver volume (%RLV) ≥ 40%.
* No tumor invasion in primary branch of portal vein, hepatic vein, or inferior vena cava.
* No other anti-tumor therapy received before the treatment.
* No metastasis in lymphnode or other organs.
* Written consent inform assigned.
Exclusion Criteria
* Intraoperative findings of tumor rupture，extrahepatic tumor or lymphnode metastasis.
* Tumor invasion in primary branch of portal vein, hepatic vein, or inferior vena cava.
18 Years
65 Years
ALL
No
Sponsors
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Southwest Hospital, China
OTHER
Responsible Party
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Li Xiaowu,MD
Dr.Xiaowu Li
Principal Investigators
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Xiaowu Li, MD-Ph D
Role: STUDY_DIRECTOR
Institute of hepatobiliry surgery,Southwest hospital
Locations
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Institute of Hepatobiliry surgery,Southwest Hospital
Chongqing, Chongqing Municipality, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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SWHB2013-005
Identifier Type: -
Identifier Source: org_study_id