Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
80 participants
OBSERVATIONAL
2021-01-31
2022-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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GROUP 1
Group 1 (patients with PD) All participants will be subjected to thorough history taking, full clinical and neurological examination. Diagnosis of PD by using Brain Bank Criteria for diagnosis of Parkinson Disease , assessment of the severity of PD by using PDRS and evaluation of cognitive functions using MMSE.
SHMT1 polymorphism
It is to identify the role of SHMT1polymorphism in PD and examine the relationship between it and Severity of PD.
Group 2
Group 2 (controls) All participants will be subjected to thorough history taking, full clinical and neurological examination.
SHMT1 polymorphism
It is to identify the role of SHMT1polymorphism in PD and examine the relationship between it and Severity of PD.
Interventions
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SHMT1 polymorphism
It is to identify the role of SHMT1polymorphism in PD and examine the relationship between it and Severity of PD.
Eligibility Criteria
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Inclusion Criteria
* Patients with PD diagnosed according to the United Kingdom Parkinson's Disease Society Brain Bank (UK PDS Brain Bank diagnostic criteria)
Exclusion Criteria
* Patients with secondary parkinsonism
* Patients with other chronic comorbidities (renal, hepatic, and endocrinal disturbances and chronic chest disease.)
* Past and /or present history of epilepsy.
* Patients with disturbed conscious level.
50 Years
ALL
Yes
Sponsors
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Aswan University Hospital
OTHER
Assiut University
OTHER
Responsible Party
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Effat AETony, MD
professor of internal medicine
Principal Investigators
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Abeer a tony, MD
Role: PRINCIPAL_INVESTIGATOR
Assistant professor
Locations
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Effat abdelhady tony
Asyut, , Egypt
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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aswan
Identifier Type: -
Identifier Source: org_study_id
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