Comparison of the Performance of an Optimized 3D EPI SWI Sequence and a Non-EPI QSM SWI Sequence in Detecting the Central Vein Sign in Patients With Multiple Sclerosis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-06-02

Study Completion Date

2023-05-24

Brief Summary

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Patients who have agreed to participate in the study will complete the MRI protocol as part of routine care, to which four additional 20-minute sequences will be added.

MRI of routine care in the context of MS includes at least the following sequences:

* 3D T1 TFE (2 minutes)
* T2 TSE (2 minutes)
* 3D FLAIR (3 minutes)
* SWI EPI 0.6 iso (7 minutes)

The sequences added by the search are:

* SWI non EPI QSM 6 echo (10 minutes)
* SWI EPI in resolution equivalent to non-EPI SWI (3 minutes)
* SWI EPI to TR equivalent to SWI non EPI (6 minutes)

These sequences will be acquired before or after the injection of gadolinium (if present in the examination of routine care). For examinations carried out with injection, the order of carrying out the 4 post-injection SWI sequences will be random.

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Detailed Description

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Conditions

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Multiple Sclerosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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cerebral MRI

MRI of routine care in the context of MS includes at least the following sequences:

* 3D T1 TFE (2 minutes)
* T2 TSE (2 minutes)
* 3D FLAIR (3 minutes)
* SWI EPI 0.6 iso (7 minutes)

The sequences added by the search are:

* SWI non EPI QSM 6 echo (10 minutes)
* SWI EPI in resolution equivalent to non-EPI SWI (3 minutes)
* SWI EPI to TR equivalent to SWI non EPI (6 minutes)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients over 18
* With MS defined according to the McDonald's revised clinical or radiological spatial and temporal dissemination criteria, with onset of symptoms \<5 years
* To benefit as part of care from an MRI with or without injection of gadolinium
* Express consent to participate in the study
* Affiliate or beneficiary of a social security scheme