Role of Mega Dose of Vitamin C in Critical COVID-19 Patients

NCT ID: NCT04682574

Last Updated: 2022-05-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

278 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-11-02

Study Completion Date

2022-03-10

Brief Summary

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Vitamin C (ascorbic acid) is a water-soluble vitamin having anti-inflammatory, immunomodulatory, anti-oxidative, antithrombotic and antiviral properties. Considering these effects vitamin C should have beneficial impact in patients suffering from sepsis and acute respiratory distress syndrome (ARDS). The current study is designed to assess the beneficial effects of Vitamin C in COVID-19 infected patients.

Detailed Description

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Conditions

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Corona Virus Infection

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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vitamin C

The dose would be 30 grams a day (10 grams TDS) for 3 days with standard treatment

Group Type ACTIVE_COMPARATOR

Vitamin C

Intervention Type DRUG

mega dose is given to the selected critically ill patients

Placebo

Distill water in the same dose with same standard treatment

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Vitamin C

mega dose is given to the selected critically ill patients

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

critically ill patients admitted in ICU

Exclusion Criteria

allergic to Vitamin C didnt given the consent
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Lahore

OTHER

Sponsor Role lead

Responsible Party

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Muhammad Mansoor Hafeez

Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Bahria Town International Hospital

Lahore, Punjab Province, Pakistan

Site Status

Countries

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Pakistan

Other Identifiers

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IRBEC/BIH/09-2020

Identifier Type: -

Identifier Source: org_study_id

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