Systemic Erythropoietin Injection in Patients Having Optic Atrophy

NCT ID: NCT04680143

Last Updated: 2021-07-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1/PHASE2

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-09-01

Study Completion Date

2021-03-30

Brief Summary

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The purpose of this treatment trial is to study the effect of systemic erythropoietin in patients having optic atrophy.

Detailed Description

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The purpose of this treatment trial is to study the effect of systemic erythropoietin in patients having optic atrophy. The intervention is systemic erythropoietin injections (eprax 10000 IU subcutaneous twice daily for three days).

Follow up after one month and three months by recording visual acuity and electro physiological studies.

Conditions

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Optic Atrophy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

The study included 10 patients diagnosed as post papilledemic optic atrophy that were attending Alexandria main university hospital. All patients underwent initially assessment of visual acuity, color vision, pupil reaction ,funduscopy and electrophysiological tests ( pattern visual evoked potential and pattern electroretinogram in both eyes to use data of the normal fellow eye as patients' internal control). Systemic erythropoietin injections (eprax 10000 IU subcutaneous twice daily for three days). Follow up after one month and three months by recording visual acuity and electro physiological studies.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Systemic erythropoietin injections

The study included 10 patients diagnosed as post papilledemic optic atrophy

Group Type EXPERIMENTAL

Systemic erythropoietin injection

Intervention Type DRUG

Systemic erythropoietin injections (eprax 10000 IU subcutaneous twice daily for three days).

Interventions

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Systemic erythropoietin injection

Systemic erythropoietin injections (eprax 10000 IU subcutaneous twice daily for three days).

Intervention Type DRUG

Other Intervention Names

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Eprax 10000

Eligibility Criteria

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Inclusion Criteria

* Post papilledemic optic atrophy patients

Exclusion Criteria

* Refuse to give an informed consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alexandria University

OTHER

Sponsor Role lead

Responsible Party

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Mohamed Fahmy Doheim

Prinicipal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mai ElBahwash, PhD

Role: PRINCIPAL_INVESTIGATOR

Alexandria Faculty of Medicine

Locations

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Alexandria Faculty of Medicine

Alexandria, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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0304845

Identifier Type: -

Identifier Source: org_study_id

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