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Short Term Refractive and Ocular Parameter Changes After Topical Atropine

NCT ID: NCT03839888

Last Updated: 2019-02-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

96 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-01-01

Study Completion Date

2015-12-31

Brief Summary

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In order we had designed a prospective clinical trial. Spherical equivalent refractive error (SER), axial length (AL), mean keratometric value (Mean-K), anterior chamber depth (ACD), and intraocular pressure (IOP) were measured at baseline and one week after topical use of 0.125% atropine. Postcycloplegic changes of refractive error and ocular parameters were evaluated, and their correlations were analyzed with multiple linear regression models.

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Detailed Description

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Conditions

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Myopia, Left Eye

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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0.125% atropine group

patients used the 0.125 % atropine eyedrop every night before sleep for 7 days

Group Type EXPERIMENTAL

0.125% Atropine

Intervention Type DRUG

patients used 0.125% atropine eyedrop per night before sleep for 7 days.

Interventions

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0.125% Atropine

patients used 0.125% atropine eyedrop per night before sleep for 7 days.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients who had an SER of -0.5 diopters or less in their eyes.

Exclusion Criteria

* Patients who had already been undergoing cycloplegic treatment for myopia before.
Minimum Eligible Age

3 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

References

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Ho MC, Hsieh YT, Shen EP, Hsu WC, Cheng HC. Short-term refractive and ocular parameter changes after topical atropine. Taiwan J Ophthalmol. 2019 Feb 20;10(2):111-115. doi: 10.4103/tjo.tjo_110_18. eCollection 2020 Apr-Jun.

Reference Type DERIVED
PMID: 32874839 (View on PubMed)

Other Identifiers

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BuddhistTCGHTaipei2

Identifier Type: -

Identifier Source: org_study_id

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