Role of Anterior Segment Optical Coherence Tomography in Infectious Keratitis

NCT ID: NCT04969640

Last Updated: 2023-03-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

23 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-07-01

Study Completion Date

2021-12-31

Brief Summary

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To evaluate the role of anterior segment optical coherence tomography in follow up of infectious keratitis and assessment of response to treatment.

Detailed Description

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50 patients with proven infectious keratitis clinically will be included in the study.

The following will be performed for all patients in initial visit and follow up:

* Slit lamp examination and photography.
* Visual acuity assessment.
* Anterior segment optical coherence tomography.

1. The central corneal thickness (CCT) (extracted from pachymetry map),
2. Minimal corneal thickness (MCT) (extracted from pachymetry map)
3. Corneal thickness at the site of the lesion (CTL) (extracted from pachymetry map or the sum of STL+ CETL)
4. Stromal thickness at the center of the lesion (STL) stromal lesion (extracted from stromal map)
5. Corneal epithelial thickness over the stromal lesion (CETL) at the center of the lesion (extracted from epithelial map)

Conditions

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Infective Keratitis

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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infective keratitis

50 cases with infectious keratitis (any age) either received medical treatment or not, attending to our department will be included in the study.

Optical coherence tomography

Intervention Type OTHER

Anterior segment optical coherence tomography examination of corneas with infective keratitis

Interventions

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Optical coherence tomography

Anterior segment optical coherence tomography examination of corneas with infective keratitis

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Any case with infectious keratitis (any age) either received medical treatment or not, attending to our department will be included in the study.

Exclusion Criteria

* Cases with healed infectious keratitis.
* Cases presented from the start with severe corneal affection and melting.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Minia University

OTHER

Sponsor Role lead

Responsible Party

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Ahemd Abdelghany

Assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ahmed Abdelghany, ASS PROF

Role: PRINCIPAL_INVESTIGATOR

Minia University

Locations

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Faculty of Medicine

Minya, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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43:6/2021

Identifier Type: -

Identifier Source: org_study_id

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