Genetic Studies in Familial Dementia

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

4884 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-06-01

Study Completion Date

2024-10-29

Brief Summary

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The purpose of this study is to identify genetic factors that contribute to or cause dementia (loss of memory) and related disorders across all ages and ethnic groups. This includes a number of neurological diseases such as early and late-onset Alzheimer disease, mild cognitive impairment, and other dementias.

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Detailed Description

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Conditions

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Dementia of Alzheimer Type Alzheimer Disease, Late Onset Alzheimer Disease, Early Onset Mild Cognitive Impairment Dementia

Study Groups

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Cognitive Control

Participants in this group are cognitively intact.

No interventions assigned to this group

Mild Cognitive Impairment

Participants in this group have mild cognitive impairment.

No interventions assigned to this group

Dementia Group

Participants in this group have dementia.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. 18 years and older
2. Patients diagnosed with dementia, their family members and unrelated healthy controls without dementia.

Exclusion Criteria

1\. Individuals with competing diagnosis such as: Amyotrophic lateral sclerosis, Frontotemporal lobar degeneration, Multiple system atrophy, Corticobasal degeneration, Progressive Supranuclear Palsy, Huntington's disease, traumatic brain injury, drug or alcohol abuse, or schizophrenia, etc. (unless family members of a dementia affected individual).

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes