Boarding Ring Glasses Versus Placebo Glasses or Not Glasses in the Treatment of Vestibular Neuritis

NCT ID: NCT04678167

Last Updated: 2023-07-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-10

Study Completion Date

2027-03-10

Brief Summary

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Vestibular neuritis is a brutal and continuous dizzying syndrome of peripheral (vestibular) origin without cochlear or other associated involvement. Specifically, vestibular neuritis is inflammation of the nerve that innervates the vestibular canals (the inner ear). It is characterized by the sudden onset of intense and prolonged vertigo accompanied by postural imbalance, nausea and vomiting, without hearing impairment or other neurological symptoms. Vestibular neuritis is the second cause of peripheral vertigo after benign paroxysmal positional vertigo. It represents approximately 7% of patients consulting for vertigo. The purpose of this study is to evaluate if wearing Boarding Ring glasses can be accelerated vestibular compensation.

Detailed Description

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Conditions

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Vestibular Neuritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

The randomization list is established by the Brest CHRU data management unit before the start of the trial. Based on a ratio (1:1:1) with stratification on the center.
Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Investigators
Only the investigator carrying out the follow-up consultations is blind.

After examination by the ENT specialist (otorhinolaryngologist) who will diagnose vestibular neuritis, the patient will be randomized into one of three groups. The clinical follow-up will be performed by another practitioner, who will not know in which arm the patient is included (the patient will come to the consultation without his glasses). Only the practitioner who realized the randomization and the patient will have information about the arm in which they are located.

Study Groups

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Boarding ring glasses

Realization of the following examinations WITH Boarding ring glasses :

* caloric tests,
* measurement of the speed of Nystagmus,
* angle of deviation in Fukuda,
* Alexander's degree of nystagmus,
* EHTEV and EEV questionnaires,
* anxiety VAS

Group Type EXPERIMENTAL

Caloric test

Intervention Type DIAGNOSTIC_TEST

Lying, patientwill be placed so that he can introduce water (hot then cold) into his external ear canal. It is the reaction of the vestibular system (sensory organ responsible for balance) which is then measured with a helmet placed over his eyes and which measures the nystagmus (movement of the eye) which reflects vestibular activity.

Measurement of the speed of Nystagmus

Intervention Type DIAGNOSTIC_TEST

A helmet with an infrared camera will be placed in front of patient eyes. This will allow visualizing on screen and measuring eye movements spontaneous or induced in the dark by various tests.

Angle of deviation at Fukuda

Intervention Type DIAGNOSTIC_TEST

The patient will be asked to trample on the spot (30 steps) with the indexes pointed forward. In the event of vestibular asymmetry, the patient turns at a varying angle to the right or to the left. This will then measure what is called the angle of deflection of the fukuda.

Alexander's degree of nystagmus

Intervention Type DIAGNOSTIC_TEST

there are 3 degrees:

* Degree I: nystagmus that exists only when the eyes are turned to the right.
* Degree II: also exists when the eyes are to the right or to the front.
* Degree Ill: exists when the eyes are on the right, front, or left

EHTEV questionnaire

Intervention Type OTHER

Handicap Scale for Balance Disorders and Vertigo

EEV questionnaire

Intervention Type OTHER

European Vertigo Assessment Questionnaire

anxiety VAS

Intervention Type OTHER

visual analog scale of anxiety

Placebo glasses

Realization of the following examinations WITH Placebo glasses :

* caloric tests,
* measurement of the speed of Nystagmus,
* angle of deviation in Fukuda,
* Alexander's degree of nystagmus,
* EHTEV and EEV questionnaires,
* anxiety VAS

Group Type PLACEBO_COMPARATOR

Caloric test

Intervention Type DIAGNOSTIC_TEST

Lying, patientwill be placed so that he can introduce water (hot then cold) into his external ear canal. It is the reaction of the vestibular system (sensory organ responsible for balance) which is then measured with a helmet placed over his eyes and which measures the nystagmus (movement of the eye) which reflects vestibular activity.

Measurement of the speed of Nystagmus

Intervention Type DIAGNOSTIC_TEST

A helmet with an infrared camera will be placed in front of patient eyes. This will allow visualizing on screen and measuring eye movements spontaneous or induced in the dark by various tests.

Angle of deviation at Fukuda

Intervention Type DIAGNOSTIC_TEST

The patient will be asked to trample on the spot (30 steps) with the indexes pointed forward. In the event of vestibular asymmetry, the patient turns at a varying angle to the right or to the left. This will then measure what is called the angle of deflection of the fukuda.

Alexander's degree of nystagmus

Intervention Type DIAGNOSTIC_TEST

there are 3 degrees:

* Degree I: nystagmus that exists only when the eyes are turned to the right.
* Degree II: also exists when the eyes are to the right or to the front.
* Degree Ill: exists when the eyes are on the right, front, or left

EHTEV questionnaire

Intervention Type OTHER

Handicap Scale for Balance Disorders and Vertigo

EEV questionnaire

Intervention Type OTHER

European Vertigo Assessment Questionnaire

anxiety VAS

Intervention Type OTHER

visual analog scale of anxiety

No glasses

Realization of the following examinations WITHOUT glasses :

* caloric tests,
* measurement of the speed of Nystagmus,
* angle of deviation in Fukuda,
* Alexander's degree of nystagmus,
* EHTEV and EEV questionnaires,
* anxiety VAS

Group Type OTHER

Caloric test

Intervention Type DIAGNOSTIC_TEST

Lying, patientwill be placed so that he can introduce water (hot then cold) into his external ear canal. It is the reaction of the vestibular system (sensory organ responsible for balance) which is then measured with a helmet placed over his eyes and which measures the nystagmus (movement of the eye) which reflects vestibular activity.

Measurement of the speed of Nystagmus

Intervention Type DIAGNOSTIC_TEST

A helmet with an infrared camera will be placed in front of patient eyes. This will allow visualizing on screen and measuring eye movements spontaneous or induced in the dark by various tests.

Angle of deviation at Fukuda

Intervention Type DIAGNOSTIC_TEST

The patient will be asked to trample on the spot (30 steps) with the indexes pointed forward. In the event of vestibular asymmetry, the patient turns at a varying angle to the right or to the left. This will then measure what is called the angle of deflection of the fukuda.

Alexander's degree of nystagmus

Intervention Type DIAGNOSTIC_TEST

there are 3 degrees:

* Degree I: nystagmus that exists only when the eyes are turned to the right.
* Degree II: also exists when the eyes are to the right or to the front.
* Degree Ill: exists when the eyes are on the right, front, or left

EHTEV questionnaire

Intervention Type OTHER

Handicap Scale for Balance Disorders and Vertigo

EEV questionnaire

Intervention Type OTHER

European Vertigo Assessment Questionnaire

anxiety VAS

Intervention Type OTHER

visual analog scale of anxiety

Interventions

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Caloric test

Lying, patientwill be placed so that he can introduce water (hot then cold) into his external ear canal. It is the reaction of the vestibular system (sensory organ responsible for balance) which is then measured with a helmet placed over his eyes and which measures the nystagmus (movement of the eye) which reflects vestibular activity.

Intervention Type DIAGNOSTIC_TEST

Measurement of the speed of Nystagmus

A helmet with an infrared camera will be placed in front of patient eyes. This will allow visualizing on screen and measuring eye movements spontaneous or induced in the dark by various tests.

Intervention Type DIAGNOSTIC_TEST

Angle of deviation at Fukuda

The patient will be asked to trample on the spot (30 steps) with the indexes pointed forward. In the event of vestibular asymmetry, the patient turns at a varying angle to the right or to the left. This will then measure what is called the angle of deflection of the fukuda.

Intervention Type DIAGNOSTIC_TEST

Alexander's degree of nystagmus

there are 3 degrees:

* Degree I: nystagmus that exists only when the eyes are turned to the right.
* Degree II: also exists when the eyes are to the right or to the front.
* Degree Ill: exists when the eyes are on the right, front, or left

Intervention Type DIAGNOSTIC_TEST

EHTEV questionnaire

Handicap Scale for Balance Disorders and Vertigo

Intervention Type OTHER

EEV questionnaire

European Vertigo Assessment Questionnaire

Intervention Type OTHER

anxiety VAS

visual analog scale of anxiety

Intervention Type OTHER

Other Intervention Names

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Barany test

Eligibility Criteria

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Inclusion Criteria

* adult patients,
* patient with vestibular neuritis defined by appearance of continuous rotating vertigo with nausea
* patient with spontaneous horizonto-rotating nystagmus beating towards the healthy ear
* patient with a postural deviation towards the affected ear;
* vestibular hyporeflexia measured at the caloric tests greater than 25%
* patient who has given free, enlighten and written consent

Exclusion Criteria

* patient with a history of vertigo of vestibular origin or with vertigo developing for more than 4 days
* patient with associated hearing loss or tinnitus
* patient with an motor ocular abnormality of central origin
* patient refusal or inability to consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Brest

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean-Christophe LECLERE, Dr

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Brest

Locations

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CHU de Brest

Brest, , France

Site Status RECRUITING

CH Pays de Morlaix

Morlaix, , France

Site Status TERMINATED

CH de Cornouaille Quimper

Quimper, , France

Site Status NOT_YET_RECRUITING

Countries

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France

Central Contacts

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Jean-Christophe LECLERE, Dr

Role: CONTACT

02.98.22.33.78

Facility Contacts

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Jean-Christophe LECLERE, Dr

Role: primary

02.98.22.33.78

Charlotte MISTRETTA

Role: primary

Other Identifiers

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29BRC20.0040

Identifier Type: -

Identifier Source: org_study_id

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