Quantified Analysis of Neuronal Recovery Using Myelin Imaging After Robot Assisted Upper Arm Training in Subacute Stroke Patients
NCT ID: NCT04651322
Last Updated: 2020-12-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
24 participants
INTERVENTIONAL
2019-03-01
2021-06-30
Brief Summary
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* Development of brain imaging technology to improve understanding of brain plasticity during rehabilitation and to improve the efficiency of rehabilitation treatment for people with brain injury. ○ Development of the latest brain function image analysis algorithm and data processing technology
* Development of new technology for imaging brain plasticity in addition to existing functional imaging technology and diffuse imaging technology (Example: Myelinated brain imaging technology, susceptibility imaging (SWI) technology)
* Development of image reconstruction software technology using new image technology
* Multi-image and repeated shot data processing technology, wheat analysis technology development (Example: 3D registration technology, automated segmentation technology)
* Conducted clinical research on clinical quantitative evaluation of brain plasticity due to rehabilitation treatment
* Recruitment of a group of patients for pursuing plasticity through rehabilitation among stroke patients (estimating the number of sample patients by setting a specific patient group and analyzing statistical power)
* Image-based brain change analysis through patient rehabilitation and before and after imaging
* Comparative analysis through securing a control group and activating the control group. Derivation of clinical relevance through comparison with rehabilitation process
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Training group
upper robot Robot assisted upper arm training(RAT)
The training group received an additional upper robot Robot assisted upper arm training(RAT) with Armeopower® 5 times per week for 4weeks.
\*Robot Assisted Arm training + Conventional occupational therapy
Control group
Conventional therapy
The control group received the usual conventional therapy \*Only Conventional occupational therapy
Interventions
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upper robot Robot assisted upper arm training(RAT)
The training group received an additional upper robot Robot assisted upper arm training(RAT) with Armeopower® 5 times per week for 4weeks.
\*Robot Assisted Arm training + Conventional occupational therapy
Conventional therapy
The control group received the usual conventional therapy \*Only Conventional occupational therapy
Eligibility Criteria
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Inclusion Criteria
2. have FMA score greater than 7
3. have confirmed that the integrity of the Corticospinal Tract (CST) is preserved in Diffusion Tensor Imaging (DTI) taken using
4. over 20 years of age
5. can understand and participated in study
6. consented to this study in writing or verbally
Exclusion Criteria
2. past history of stroke
3. past history of Musculoskeletal disease or history of Neurological diseases
4. have a history of injury to the upper limb and upper chest, surgery, or peripheral nerve damage
5. have skin ulcers or skin diseases such as open wounds that have difficulty applying RAT
6. Pregnant woman
7. If it is judged that this clinical participation is not appropriate according to the judgment of medical doctor
20 Years
90 Years
ALL
No
Sponsors
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Yonsei University
OTHER
Responsible Party
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Principal Investigators
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Deog Young Kim
Role: PRINCIPAL_INVESTIGATOR
Severance Hospital
Locations
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Yonsei Severance Hospital
Seoul, , South Korea
Countries
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Central Contacts
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Facility Contacts
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Deog Young Kim
Role: primary
Other Identifiers
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1-2019-0023
Identifier Type: -
Identifier Source: org_study_id