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HIIT for Inflammatory Rheumatic Disease: Man vs Machine

NCT ID: NCT04649528

Last Updated: 2020-12-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

49 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-01-03

Study Completion Date

2018-03-23

Brief Summary

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The purpose of this study is to compare two modes of delivering high-intensity interval training (HIIT) in a population with inflammatory rheumatic disease over 10 weeks. One group will recieved HIIT supervised by a healthcare professional, the other group will perform self-monitored HITT with guidance by a smarthpone application.

Detailed Description

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People with inflammatory rheumatic diseases (IRS) such as rheumatoid arthritis (RA), spondyloarthritis (SpA) and systemic lupus erythematosus (SLE) have been shown to have reduced cardiovascular fitness and quality of life than the general population. Cardiovascular health is the single most important factor of total mortality. It has been shown previously that individuals with IRS tolerate both endurance training, resulting in improvement in function and cardiovascular health while also having a positive effect on disease activity measured through inflammation, pain, joint health and fatigue. In recent years, studies have also been conducted that demonstrate both the safety and effect of aerobic 4x4min high-intensity interval training (HIIT) for patients with IRS.

This study will involve an intervention period consisting of 20 HIIT sessions. Participants are randomized into one of two training groups. One group will perform HIIT under the supervision of a healthcare professional. The other group will perform the same HIIT training with identical instructions, however they will be self-monitored with the aid and guidance of a mobilephone application.

The purpose of the intervention is to increase maximum oxygen uptake and improve quality of life. The intervention period will consist of 2 weekly sessions lasting approximately 35 minutes performed on non-consecutive days. The endurance training will consist of 4 intervals of 4 minutes duration, separated by a 3-4 minute active break and follows the principle of intensive aerobic interval training. Before and after the training period, identical testing (approximately 30-40 min) will be performed by both intervention groups. The testing will include measurements of work economy and maximal oxygen uptake in an endurance test. Additionally, quality of life questionnaires will be obtained.

Conditions

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Inflammatory Rheumatism

Keywords

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VO2max Cardiovascular health Quality of life Endurance exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized trial
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators
The exercise physiologist performing the maximal oxygen uptake pre and posttests was blinded with reguards to which intervention group the participants had been assigned.

Study Groups

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Supervised HIIT

Exercise intervention, 20 supervised by healthcare professional

Group Type EXPERIMENTAL

Effective endurance 4x4 training - Supervised

Intervention Type BEHAVIORAL

Exercise intervention utilizing 4x4min aerobic high-intensity interval training

APP HIIT

Exercise intervention, 20 self-monitored assisted by a mobilephone application

Group Type EXPERIMENTAL

Effective endurance 4x4 training - APP

Intervention Type DEVICE

Exercise intervention utilizing 4x4min aerobic high-intensity interval training

Interventions

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Effective endurance 4x4 training - Supervised

Exercise intervention utilizing 4x4min aerobic high-intensity interval training

Intervention Type BEHAVIORAL

Effective endurance 4x4 training - APP

Exercise intervention utilizing 4x4min aerobic high-intensity interval training

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

\- Inflammatory rheumatic disease

Exclusion Criteria

* Inability to complete the testing procedures
* Pregancy
* Not able to perform exercise intervention
* Planed surgeries or other plans during initial exercise intervention period than directly will effect the testing or training.
* Access to a smartphone
* Less than 80% compliance of planned training sessions
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Molde University College

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jan Helgerud, PhD

Role: PRINCIPAL_INVESTIGATOR

Norwegian University of Science and Technology

Locations

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Myworkout - Medical Rehabilitation Clinic

Trondheim, Please Select, Norway

Site Status

Countries

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Norway

References

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Haglo H, Wang E, Berg OK, Hoff J, Helgerud J. Smartphone-Assisted High-Intensity Interval Training in Inflammatory Rheumatic Disease Patients: Randomized Controlled Trial. JMIR Mhealth Uhealth. 2021 Oct 21;9(10):e28124. doi: 10.2196/28124.

Reference Type DERIVED
PMID: 34673536 (View on PubMed)

Other Identifiers

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HHRevma1

Identifier Type: -

Identifier Source: org_study_id