Interval Training Study in Psoriatic Arthritis

NCT ID: NCT02995460

Last Updated: 2018-11-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

67 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-01-31

Study Completion Date

2015-12-31

Brief Summary

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Psoriatic arthritis is a chronical inflammatory disease characterized by pain and reduced physical function. Patients have a higher risk of cardiovascular disease and a higher body mass index.

A pilot study in patients with rheumatoid arthritis has shown positive effect on inflammation after 12 weeks of high-intensity interval training.

The primary aim of this study is to determine whether high-intensity interval training affects the disease activity in psoriatic arthritis. This intervention is believed to result in benefits in terms of inflammation, body composition and risk factors for cardiovascular disease.

Detailed Description

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Conditions

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Psoriatic Arthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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interval training

4x4 high intensity interval training was performed on a stationary bicycle with a supervisor twice a week and by one self-training a week.

Group Type EXPERIMENTAL

interval training

Intervention Type BEHAVIORAL

4x4 high intensity interval training

controls

No change in diet and training habits

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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interval training

4x4 high intensity interval training

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* fulfilling the CASPAR criteria of psoriatic arthritis
* ability to exercise.

Exclusion Criteria

* Inability to exercise
* very high disease Activity
* unstable ischemic cardiovascular disease
* severe pulmonary disease
* pregnancy
* breastfeeding
* drug- and alcohol addictions
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Helse Midt-Norge

OTHER

Sponsor Role collaborator

Norwegian University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Siri Forsmo, md prof

Role: STUDY_DIRECTOR

Norwegian University of Science and Technology

References

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Thomsen RS, Nilsen TIL, Haugeberg G, Bye A, Kavanaugh A, Hoff M. Impact of High-Intensity Interval Training on Disease Activity and Disease in Patients With Psoriatic Arthritis: A Randomized Controlled Trial. Arthritis Care Res (Hoboken). 2019 Apr;71(4):530-537. doi: 10.1002/acr.23614.

Reference Type RESULT
PMID: 29882634 (View on PubMed)

Thomsen RS, Nilsen TIL, Haugeberg G, Bye A, Kavanaugh A, Hoff M. Effect of high-intensity interval training on cardiovascular disease risk factors and body composition in psoriatic arthritis: a randomised controlled trial. RMD Open. 2018 Oct 11;4(2):e000729. doi: 10.1136/rmdopen-2018-000729. eCollection 2018.

Reference Type RESULT
PMID: 30402265 (View on PubMed)

Thomsen RS, Nilsen TIL, Haugeberg G, Sitter B, Kavanaugh A, Pedersen SJ, Hoff M. Changes of inflammation in patients with psoriatic arthritis after high intensity interval training assessed by ultrasound and MRI, a randomized controlled trial. BMC Musculoskelet Disord. 2023 Sep 19;24(1):743. doi: 10.1186/s12891-023-06871-3.

Reference Type DERIVED
PMID: 37726677 (View on PubMed)

Chronaiou I, Thomsen RS, Huuse EM, Euceda LR, Pedersen SJ, Hoff M, Sitter B. Quantifying bone marrow inflammatory edema in the spine and sacroiliac joints with thresholding. BMC Musculoskelet Disord. 2017 Nov 28;18(1):497. doi: 10.1186/s12891-017-1861-1.

Reference Type DERIVED
PMID: 29179748 (View on PubMed)

Other Identifiers

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2012/1646

Identifier Type: -

Identifier Source: org_study_id

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