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Surgery for Locally Advanced Colon Cancer: is it Worth it? A Multicenter Retrospective Analysis.

NCT ID: NCT04646772

Last Updated: 2020-12-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-01

Study Completion Date

2021-06-30

Brief Summary

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The aim of the present study is to assess the post-operative outcomes (morbidity and mortality) in relation to preoperative data and the oncological outcomes (overall and disease-free survival) in patients with a locally advanced colon cancer (LACC) with the necessity of a multivisceral resection (MVR).

Detailed Description

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All patients that meet the inclusion criteria will be registered in a retrospective database from 2014 to 2019 (5 years) Data will be reported for every patients with colon cancer to have had either a resection of another organ or structure in addition to resection of the primary tumor, or to have had a T4 (a or b) tumour on postoperative histopathology.

Data included are patient demographics, ASA score, tumor localization, preoperative imaging, neoadjuvant treatments, type of bowel resection and adjacent organs resected, tecnique (laparoscopic/laparotomic), postoperative complications and 30-day mortality, histopathology data including TNM scoring, completeness of surgical procedure (R0 to R2) and infiltration of tumor cells in resected tissues, adjuvant oncological treatments, and long term follow-up data on local and distant recurrence and survival.

Conditions

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Malignant Neoplasm of Large Intestine TNM Staging Primary Tumor (T) T4

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Interventions

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Multivisceral resection

Multivisceral resection for locally advanced colon cancer.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* \> 18 aa
* Patients with a locally advanced colon cancer (LACC) with the necessity of a multivisceral resection (MVR).

Exclusion Criteria

* Stage IV
* Rectal cancer
* Emergency surgery (\<48 hours from admission)
* ASA \> III
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Santo Spirito Hospital, Italy

OTHER

Sponsor Role lead

Responsible Party

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Francesca Cravero

Dirigente Medico I livello Chirurgia Generale

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Other Identifiers

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LACC Trial

Identifier Type: -

Identifier Source: org_study_id