French Cohort of COVID-19 Patients With Post-intensive Care Syndrome

NCT ID: NCT04590170

Last Updated: 2025-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

85 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-10-30

Study Completion Date

2022-10-31

Brief Summary

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The purpose of this study is to describe post-intensive care syndrome (PICS) of patients surviving to coronavirus disease 2019 (COVID19) and their rehabilitation and recovery process from hospital to home return

Detailed Description

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The novel coronavirus, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the COVID-19 emerged in December 2019 and was declared pandemic in March 2020.

Although the majority of reported COVID-19 cases are mild, approximatively 5% of patients require a stay in intensive care unit, with mechanical ventilation.

Post intensive care syndrome (PICS) consists of physical, cognitive and psychological dysfunctions.

Little is known about the rate and clinical presentations of PCIS among patients surviving to COVID-19.

The objective of this study is to describe the clinical manifestations of PCIS in COVID-19 patients, and their rehabilitation process until home return.

Conditions

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Covid19

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients with Covid19 infection

Patients with Covid19 infection

Post-intensive Care unit syndrome

Intervention Type BEHAVIORAL

Post-intensive Care unit syndrome after an intensive care unit stay for the COVID19

Control group

Asymptomatic group

Spatiotemporal measurements of walking

Intervention Type OTHER

Spatiotemporal measurements of walking in asymptomatic participants from the general population.

Interventions

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Post-intensive Care unit syndrome

Post-intensive Care unit syndrome after an intensive care unit stay for the COVID19

Intervention Type BEHAVIORAL

Spatiotemporal measurements of walking

Spatiotemporal measurements of walking in asymptomatic participants from the general population.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* COVID 19 infection (PCR or CT-scan)
* ICU stay requiring mechanical ventilation
* Age ≥18 years old


* Age ≥ 18 years old
* Able to walk without technical assistance,
* Having no orthopedic or neurological disorder likely to disturb balance and walking
* Have not had a severe form of Covid 19 disease in the last 12 months
* Collection of non-opposition

Exclusion Criteria

\- Inability to give consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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URC-CIC Paris Descartes Necker Cochin

OTHER

Sponsor Role collaborator

Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Camille DASTE, MD

Role: PRINCIPAL_INVESTIGATOR

Study Principal Investigator

Locations

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Department of Rehabilitation, Institute of Rheumatology Cochin

Paris, Paris, France

Site Status

Department of Physical Medicine and Rehabilitation

Issy-les-Moulineaux, , France

Site Status

Countries

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France

References

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Daste C, Ficarra S, Dumitrache A, Cariou A, Lefebvre A, Pene F, Roche N, Roren A, Thery C, Vidal J, Nguyen C, Rannou F, Lefevre-Colau MM. Post-intensive care syndrome in patients surviving COVID-19. Ann Phys Rehabil Med. 2021 Nov;64(6):101549. doi: 10.1016/j.rehab.2021.101549. Epub 2021 Jun 26. No abstract available.

Reference Type BACKGROUND
PMID: 34182168 (View on PubMed)

Other Identifiers

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APHP200812

Identifier Type: -

Identifier Source: org_study_id

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