The Role of OCTA in Patients Affected by Beta Thalassemia
NCT ID: NCT04582110
Last Updated: 2021-02-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
82 participants
OBSERVATIONAL
2019-10-01
2020-02-28
Brief Summary
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Detailed Description
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The study investigated the changes in retinal and choriocapillaris vascular features using optical coherence tomography angiography, a novel and noninvasive diagnostic technique that allows a detailed analysis of retinal and choriocapillaris blood flow.
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Patients with Beta Thalassemia
Patients with previous diagnosis of Beta Thalassemia
Optical coherence tomography angiography
Each subject underwent Optical coherence tomography angiography (a non-invasive, fast, diagnostic imaging technique)
Control Group
Healthy fellow eyes without actual and previous ocular trauma
Optical coherence tomography angiography
Each subject underwent Optical coherence tomography angiography (a non-invasive, fast, diagnostic imaging technique)
Interventions
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Optical coherence tomography angiography
Each subject underwent Optical coherence tomography angiography (a non-invasive, fast, diagnostic imaging technique)
Eligibility Criteria
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Inclusion Criteria
* diagnosis of Beta Thalassemia
* absence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
* absence of significant lens opacities, low-quality OCT and OCT-A images.
Exclusion Criteria
* absence of diagnosis of Beta Thalassemia
* presence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
* presence of significant lens opacities, low-quality OCT and OCT-A images.
35 Years
50 Years
ALL
Yes
Sponsors
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Federico II University
OTHER
Responsible Party
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Gilda Cennamo
Principal Investigator
Locations
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University of Naples "Federico II"
Naples, , Italy
Countries
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Other Identifiers
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1002/19
Identifier Type: -
Identifier Source: org_study_id
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