Dermatological Abnormalities in Beta-thalassemia Major

NCT ID: NCT03894605

Last Updated: 2019-03-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

125 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-02

Study Completion Date

2021-04-02

Brief Summary

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to study the frequency and pattern of dermatological abnormalities in egyptian childern with beta thalassemia.relationof abnormalities to duration of disease and frequency of transfusion

Detailed Description

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thalassemia refers to agroup of inherited disease characterized by decreased or absent synthesis of normal globin .skinvdisorders are usually neglected and frequently underdiagnosed among these patients.skin disease specially pruritus and xerosis are observed highly frequently in patients with beta-thalassemia.pityriasis alba is arelatively common skin disorder.the trophic skin changes and leg ulcers occurred after the age of 15 years

Conditions

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Beta-Thalassemia

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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thalassemia

thalassemic patient use chelator and thaladssemic patient with frequent blood transfusion

Intervention Type DEVICE

Eligibility Criteria

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Exclusion Criteria

* patient with other hemolytic anemia. childern with any abnormalities prior to the diagnosis of thalassemi
Minimum Eligible Age

2 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Neveen Mamdoh Farag

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Alsayed khalil Abd elkareem, Professor

Role: CONTACT

01060805170

Mostafa Mohamed, Lecturer

Role: CONTACT

01006244311

References

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Cao A, Galanello R. Beta-thalassemia. Genet Med. 2010 Feb;12(2):61-76. doi: 10.1097/GIM.0b013e3181cd68ed.

Reference Type BACKGROUND
PMID: 20098328 (View on PubMed)

El-Dash H, Adel S. Cutaneous manifestations in Egyptian children with beta-thalassemia major: Relationship with serum ferritin, thyroid profile, and treatment modalities. Pediatr Dermatol. 2018 Sep;35(5):639-643. doi: 10.1111/pde.13570. Epub 2018 Jun 26.

Reference Type RESULT
PMID: 29943859 (View on PubMed)

Dogramaci AC, Savas N, Ozer B, Duran N. Skin diseases in patients with beta-thalassemia major. Int J Dermatol. 2009 Oct;48(10):1057-61. doi: 10.1111/j.1365-4632.2009.04176.x.

Reference Type RESULT
PMID: 19785086 (View on PubMed)

CHANG PY, KUO CL, KHOO FY. The anatomic distribution of the lesions in pulmonary tuberculosis. Med Abstr. 1945 Oct;63A:237-43. No abstract available.

Reference Type RESULT
PMID: 20997138 (View on PubMed)

Other Identifiers

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DBTM

Identifier Type: -

Identifier Source: org_study_id

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