B-Thalasaemia Trait and Its Possible Cardioprotective Role

NCT ID: NCT02428023

Last Updated: 2016-01-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

2500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-03-31

Study Completion Date

2017-04-30

Brief Summary

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Our purpose is to investigate whether thallasaemia trait offers protection against cardiovascular events and whether this can be applied to specific characteristics of these people ( better lipid profile , better blood pressure profile) as scientific literature suggests.

Detailed Description

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Thallasaemia is a major problem , especially in countries around the Mediterranean sea.On the other hand ,thallasaemia trait has been shown ,in a small number of studies , to have a possible protective role against CAD and stroke.These kind of studies have been contacted in Greece also ,and usually they enroll a small number of participants. In the study, investigators will enroll 2500 subjects who serve in military units in Thesally Greece. Firstly investigators will estimate the prevalence of thallasaemia trait in this population , as it is very high in this region and at the same time investigators will retrospectively record data from their personal files (which are annually recorded).

Conditions

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Beta-Thalassemia Trait Coronary Artery Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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GrThalasaemia

estimation of IMT of the carotides arteries and calcium scoring

No interventions assigned to this group

GrNormal

estimation of IMT of the carotides arteries and calcium scoring

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. voluntary participation,
2. Subjects with Thalassemia treat will be confirmed of their treat by electrophoresis -

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Maximum Eligible Age

57 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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404 General Military Hospital, Larissa

OTHER

Sponsor Role lead

Responsible Party

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ANDREANIDIS ELIAS

Director of Cardiology Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Elias Andreanidis, PhD

Role: PRINCIPAL_INVESTIGATOR

404 General Military Hospital, Larissa

Locations

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404 Military Hospital

Larissa, , Greece

Site Status RECRUITING

Countries

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Greece

Central Contacts

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Elias Andreanidis, PhD

Role: CONTACT

+3 6944570406

Maria Malliarou, PhD

Role: CONTACT

+3 6944796499

Facility Contacts

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ELIAS ANDREANIDES, PhD

Role: primary

+3 6944570406

Maria Malliarou, PhD

Role: backup

Other Identifiers

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404 General Military Hospital

Identifier Type: -

Identifier Source: org_study_id

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