Local Anesthetic as Single Shot Versus Catheter in Patients Undergoing Video Assisted Thoracoscopic Surgery
NCT ID: NCT04559347
Last Updated: 2025-06-12
Study Results
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View full resultsBasic Information
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TERMINATED
PHASE2
45 participants
INTERVENTIONAL
2020-12-10
2024-08-07
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Single Shot Liposomal Bupivacaine (EXPAREL®)/Bupivacaine
Single Shot Liposomal Bupivacaine (EXPAREL®)/Bupivacaine for erector spinae block as local anesthetic
Liposomal Bupivacaine (EXPAREL®)/Bupivacaine
Single shot for erector spinae block
Continuous catheter infusion ropivacaine
Ropivacaine (0.5% bolus followed by 0.2% infusion) using a continuous catheter for erector spinae plane block as local anesthetic
Ropivacaine (0.5% bolus followed by 0.2% infusion)
Continuous catheter infusion for erector spinae plane block
Interventions
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Liposomal Bupivacaine (EXPAREL®)/Bupivacaine
Single shot for erector spinae block
Ropivacaine (0.5% bolus followed by 0.2% infusion)
Continuous catheter infusion for erector spinae plane block
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* left ventricular ejection fraction \< 30%,
* history of drug or narcotic abuse,
* history of allergic to amide local anesthetic,
* presence of contraindication for erector spinae plane block (local skin infection, sepsis, severe coagulopathy)
* unable to provide consent,
* unable to use pain rating scales as demonstrated by verbal feedback
* preoperative chronic pain on narcotics,
* history of renal insufficiency ( Creatinine \> 1.5 mg/dl),
* preoperative mild liver impairment ( i.e. AST/ALT above 1.5 times the upper normal limit)
18 Years
ALL
No
Sponsors
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Poovendran Saththasivam
OTHER
Responsible Party
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Poovendran Saththasivam
Sponsor-Investigator
Principal Investigators
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Poovendran Saththasivam, MD
Role: PRINCIPAL_INVESTIGATOR
The Guthrie Clinic
Locations
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Robert Packer Hospital
Sayre, Pennsylvania, United States
Countries
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Provided Documents
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Document Type: Study Protocol
Document Type: Statistical Analysis Plan
Other Identifiers
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2007-48
Identifier Type: -
Identifier Source: org_study_id
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