Pulmonary Disease Requiring Ambulatory Oxygen Therapy -Resilience and Quality of Life

NCT ID: NCT04554225

Last Updated: 2023-10-26

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 43 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2017-11-01
• Study Completion Date: 2023-12-31

Brief Summary

Dyspnea is common symptom in pulmonary diseases, like chronic obstructive pulmonary disease (COPD) or other pulmonary disease. Ambulatory oxygen therapy is often prescribed to these patients. In these patients resilience, health related quality of life, life satisfaction are measured and the effect and patient satisfaction to ambulatory oxygen therapy are studied.

Detailed Description

Dyspnea is a common symptom in pulmonary disease patients, such as chronic obstructive pulmonary disease (COPD) and interstitial lung diseases. These patients often have low health-related quality of life (HRQoL) and life satisfaction (LS), and high levels of anxiety and depression.

Oxygen therapy is used in severe pulmonary diseases to improve HRQoL and prolong survival. Ambulatory oxygen therapy is prescribed to patients who become transiently hypoxemic, e.g. during exercise or normal outdoors activities. However, only 46 % of COPD patients were adherent to long-term oxygen therapy. Proper adaptation to a serious illness, such as advanced COPD and interstitial lung diseases, necessitates resilience. Resilience is an ability to adapt appropriately in difficulties in life. This ability is based on a person's psychological resources, and it can be learned and improved with time and effort. Evaluation of resilience is commonly applied in psychological examinations and research, but less attention has been paid in medical context even though resilience capacity is closely connected to recovery abilities and adaptation.

The main aim is to measure resilience in pulmonary disease patients receiving ambulatory oxygen therapy and how it correlates with other measures of HRQoL and LS. Also anxiety and depression are surveyed and satisfaction to ambulatory oxygen therapy devices and associated services.Investigators also compare the HRQoL of pulmonary disease patients receiving ambulatory oxygen therapy to an age and gender matched sample of the general population. Primary outcome measure was the proportion of patients with low resilience, and secondary outcomes were how resilience correlated with HRQoL, LS, anxiety and depression in patients prescribed ambulatory oxygen therapy.

Conditions

Pulmonary Disease

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Pulmonary disease patients

Patients with COPD or other pulmonary disease starting to use ambulatory oxygen therapy

Oxygen gas

Intervention Type: DRUG

Oxygen administered to a patient using ambulatory oxygen

Interventions

Oxygen gas

Oxygen administered to a patient using ambulatory oxygen

Intervention Type: DRUG

Other Intervention Names

ambulatory oxygen

Eligibility Criteria

Inclusion Criteria

• Patient with pulmonary disease (e.g. COPD) who has ambulatory oxygen
• Patient with pulmonary disease (e.g. COPD) who is starting to use ambulatory oxygen
• Adult patient
• Informed consent of the patient received

Exclusion Criteria

• Ambulatory oxygen prescribe for treatment of other than pulmonary disease.
• Age less than 18 years
• Dementia or other cognitive impairment that disables understanding of the study
• No informed consent

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Helsinki University Central Hospital

OTHER

Sponsor Role: collaborator

Tampere University Hospital

OTHER

Sponsor Role: collaborator

Kuopio University Hospital

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Merja Kokki, V

Role: PRINCIPAL_INVESTIGATOR

Kuopio University Hospital

Locations

Kuopio University Hospital

Kuopio, Northern Savonia, Finland

Countries

Finland

References

Isokaanta S, Kokki H, Sintonen H, Kokki M. Resilience and health-related quality of life in patients with pulmonary diseases receiving ambulatory oxygen therapy - 24-month follow-up results. BMC Pulm Med. 2025 Jul 4;25(1):326. doi: 10.1186/s12890-025-03778-8.

Reference Type: DERIVED

PMID: 40616033 (View on PubMed)

Isokaanta S, Honkalampi K, Kokki H, Sintonen H, Kokki M. Resilience and health-related quality of life in patients with pulmonary diseases receiving ambulatory oxygen therapy. BMC Pulm Med. 2021 May 1;21(1):144. doi: 10.1186/s12890-021-01515-5.

Reference Type: DERIVED

PMID: 33933036 (View on PubMed)

Other Identifiers

507A023

Identifier Type: -

Identifier Source: org_study_id