The Impact of Pulmonary Rehabilitation on Dyspnea in Chronic Obstructive Pulmonary Disease
NCT ID: NCT01513616
Last Updated: 2012-12-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
48 participants
INTERVENTIONAL
2006-11-30
2011-12-31
Brief Summary
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The main objectives of the study were:
1. To conduct and compare detailed studies of respiratory mechanics during cycle exercise before and after exercise training (EXT) compared with an untrained control group. By multiple regression analysis, the investigators will establish the main contributors to dyspnea relief after EXT.
2. To compare the magnitude of change in endurance during constant work rate cycle exercise with those measured during walk tests and the endurance shuttle walk test after EXT relative to control. To evaluate which test (constant work rate cycle, six-minute walk test, or endurance shuttle walk test) is the most sensitive test for measuring changes in endurance after EXT versus control.
3. To compare the change in standardized dyspnea ratings (Borg Scale) during constant-load cycling with a variety of other activity-related dyspnea questionnaires. To evaluate which of these measurements is the most sensitive for examining changes in perceived discomfort during exercise.
4. To evaluate the contribution of psychological factors (anxiety, fear, respiratory panic, self-efficacy) to the perceived improvement of symptoms following EXT. The investigators will use multiple regression analysis to examine associations between changes in perceived dyspnea and changes in anxiety and self-efficacy measured by validated questionnaires and Borg intensity ratings?
Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Pulmonary rehabilitation
A supervised 8-wk outpatient pulmonary rehabilitation program consisting of multi-modality exercise training and COPD self-management education.
Pulmonary rehabilitation
8-week program, 3 supervised session per week
Usual care control
An 8-wk control period consisting of usual medical care which included optimization of respiratory medications, instructions on how best to manage COPD, standard access to treatment in the event of an exacerbation, self-management education.
Pulmonary rehabilitation
8-week program, 3 supervised session per week
Usual care
An 8-week control period (includes optimization of respiratory medications, instructions on how best to manage COPD, standard access to treatment in the event of an exacerbation, self-management education)
Interventions
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Pulmonary rehabilitation
8-week program, 3 supervised session per week
Usual care
An 8-week control period (includes optimization of respiratory medications, instructions on how best to manage COPD, standard access to treatment in the event of an exacerbation, self-management education)
Eligibility Criteria
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Inclusion Criteria
* clinically stable
* presence of activity-related dyspnea (Baseline Dyspnea Index \< 9)
* 40-80 years of age
Exclusion Criteria
* body mass index \< 18 or \> 40 kg/m2
40 Years
80 Years
ALL
No
Sponsors
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Queen's University
OTHER
Responsible Party
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Dr. Denis O'Donnell
Principal Investigator
Principal Investigators
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Denis O'Donnell, MD, FRCPC
Role: PRINCIPAL_INVESTIGATOR
Queen's University and Kingston General Hospital
Locations
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Respiratory Investigation Unit at Kingston General Hospital
Kingston, Ontario, Canada
Countries
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Other Identifiers
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DMED-986-06
Identifier Type: -
Identifier Source: org_study_id