Compensatory Movements With Axon-Hook and Greifer in Transradial Amputees

NCT ID: NCT04522349

Last Updated: 2020-08-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

8 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-09-29

Study Completion Date

2017-02-14

Brief Summary

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Upper limb amputees often report musculoskeletal pain due to exaggerated shoulder abduction movements. Previous studies on prosthetic hands showed that wrist orientation contributes to reduce shoulder compensatory movements. The hypothesis of this research is that prosthetic hooks may also provide better functional outcomes when offering wrist adjustments and a design that favors a good visualization of the grips. The objective of this study is to compare shoulder abduction, manual dexterity and satisfaction when using Axon-Hook and Greifer myoelectric hooks during repetitive tasks. Shoulder abduction and manual dexterity results are also compared with the sound side.

Detailed Description

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Depending on patient's expectations, different prosthetic solutions can be offered. If prosthetic hands, being at the same time functional and aesthetic solutions, are widely used, for some professional or leisure activities, myoelectric users will have a better functional response with a non-morphologic terminal device such as a hook.

Axon-hook and Greifer are two myoelectric hooks proposed by Otto Bock HealthCare. Greifer (Myobock system) has two movable strong hooks and a wrist that can be orientated medially or laterally. Axon-Hook (Axon-Bus system) has thin hooks for a good visualization of the grip, one being fixed for more precision, and a flexible wrist that can be orientated and locked in flexion and extension position.

Previous studies on myoelectric hands showed that functionalities of prosthetic components such as type of hand or type of wrist, have an influence on compensatory movements, which can explain musculoskeletal pains. The hypothesis of the study is that Axon-Hook may reduce shoulder abduction and improve patient satisfaction. No significant difference is expected regarding manual dexterity.

This randomized corossover trial compares shoulder abduction, manual dexterity and satisfaction while using Axon-Hook and Greifer. Shoulder abduction and manual dexterity results are also compared with the sound side.

Conditions

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Transradial Amputation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

randomized crossover trial (AB/BA)
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Greifer then Axon-Hook

T0 + 2 weeks: evaluation with Greifer. T1 + 2 weeks: evaluation with Axon-Hook

Group Type ACTIVE_COMPARATOR

Greifer then Axon-Hook

Intervention Type DEVICE

Each participant is fitted with a Greifer and assessed after two weeks home-trial. Then he is fitted with Axon-Hook and assessed after two weeks home trial.

Axon-Hook then Greifer

T0 + 2 weeks: evaluation with Axon-Hook. T1 + 2 weeks: evaluation with Greifer

Group Type ACTIVE_COMPARATOR

Axon-Hook then Greifer

Intervention Type DEVICE

Each participant is fitted with a Axon-Hook and assessed after two weeks home-trial. Then he is fitted with Greifer and assessed after two weeks home trial.

Interventions

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Greifer then Axon-Hook

Each participant is fitted with a Greifer and assessed after two weeks home-trial. Then he is fitted with Axon-Hook and assessed after two weeks home trial.

Intervention Type DEVICE

Axon-Hook then Greifer

Each participant is fitted with a Axon-Hook and assessed after two weeks home-trial. Then he is fitted with Greifer and assessed after two weeks home trial.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* persons with trans-radial upper limb amputation
* persons whose amputation is acquired or congenital
* persons who regularily uses a myoelectric prosthesis and who controls it
* persons whose residual limb is stabilized, with a minimum time of six month since amputation
* persons whose profesional activity or life project justify or could justify the use of a myoelectric hook
* persons who gave their written consent to participate to the study

Exclusion Criteria

* persons under 18 years of age
* pregnant woman
* persons unable to personnaly give their consent
* persons with psychic or linguistic inability to understand instructions for the test
* persons unavailable to comply with the entire study protocol
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Euraxi Pharma

INDUSTRY

Sponsor Role collaborator

Otto Bock France SNC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Amélie TOUILLET

Role: PRINCIPAL_INVESTIGATOR

Institut Régional de Rééducation et de Réadaptation de Nancy

Locations

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Institut Régional de Rééducation et de Réadaptation

Nancy, Lorraine, France

Site Status

Countries

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France

References

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A.G. Cutti; I. Parel; M. Luchetti; E. Gruppioni; N. Rossi; G. Verni, The Psychosocial and Biomechanical Assessment of Amputees Fitted with Commercial Multi-grip Prosthetic Hands, in: Grasping the Future: Advances in Powered Upper Limb Prosthetics, BOLOGNA, VINCENZO PARENTI CASTELLI & MARCO TRONCOSSI, 2012, pp. 59 - 77

Reference Type BACKGROUND

Major MJ, Stine RL, Heckathorne CW, Fatone S, Gard SA. Comparison of range-of-motion and variability in upper body movements between transradial prosthesis users and able-bodied controls when executing goal-oriented tasks. J Neuroeng Rehabil. 2014 Sep 6;11:132. doi: 10.1186/1743-0003-11-132.

Reference Type BACKGROUND
PMID: 25192744 (View on PubMed)

Carey SL, Dubey RV, Bauer GS, Highsmith MJ. Kinematic comparison of myoelectric and body powered prostheses while performing common activities. Prosthet Orthot Int. 2009 Jun;33(2):179-86. doi: 10.1080/03093640802613229.

Reference Type BACKGROUND
PMID: 19367522 (View on PubMed)

Metzger AJ, Dromerick AW, Holley RJ, Lum PS. Characterization of compensatory trunk movements during prosthetic upper limb reaching tasks. Arch Phys Med Rehabil. 2012 Nov;93(11):2029-34. doi: 10.1016/j.apmr.2012.03.011. Epub 2012 Mar 23.

Reference Type BACKGROUND
PMID: 22449551 (View on PubMed)

Ostlie K, Franklin RJ, Skjeldal OH, Skrondal A, Magnus P. Musculoskeletal pain and overuse syndromes in adult acquired major upper-limb amputees. Arch Phys Med Rehabil. 2011 Dec;92(12):1967-1973.e1. doi: 10.1016/j.apmr.2011.06.026.

Reference Type BACKGROUND
PMID: 22133243 (View on PubMed)

Bertels T, Schmalz T, Ludwigs E. Objectifying the functional advantages of prosthetic wrist flexion. J Prosthet Orthot. 2009;21(2):74-8.

Reference Type BACKGROUND

Deijs M, Bongers RM, Ringeling-van Leusen ND, van der Sluis CK. Flexible and static wrist units in upper limb prosthesis users: functionality scores, user satisfaction and compensatory movements. J Neuroeng Rehabil. 2016 Mar 15;13:26. doi: 10.1186/s12984-016-0130-0.

Reference Type BACKGROUND
PMID: 26979272 (View on PubMed)

Resnik L, Borgia M, reliability and validity of outcome measures for upper limb amputation. JPO. 2012;24:192-201

Reference Type BACKGROUND

Hebert JS, Lewicke J, Williams TR, Vette AH. Normative data for modified Box and Blocks test measuring upper-limb function via motion capture. J Rehabil Res Dev. 2014;51(6):918-32. doi: 10.1682/JRRD.2013.10.0228.

Reference Type BACKGROUND
PMID: 25356979 (View on PubMed)

Haverkate L, Smit G, Plettenburg DH. Assessment of body-powered upper limb prostheses by able-bodied subjects, using the Box and Blocks Test and the Nine-Hole Peg Test. Prosthet Orthot Int. 2016 Feb;40(1):109-16. doi: 10.1177/0309364614554030. Epub 2014 Oct 21.

Reference Type BACKGROUND
PMID: 25336050 (View on PubMed)

Mathiowetz V, Volland G, Kashman N, Weber K. Adult norms for the Box and Block Test of manual dexterity. Am J Occup Ther. 1985 Jun;39(6):386-91. doi: 10.5014/ajot.39.6.386.

Reference Type BACKGROUND
PMID: 3160243 (View on PubMed)

Carey SL, Jason Highsmith M, Maitland ME, Dubey RV. Compensatory movements of transradial prosthesis users during common tasks. Clin Biomech (Bristol). 2008 Nov;23(9):1128-35. doi: 10.1016/j.clinbiomech.2008.05.008.

Reference Type BACKGROUND
PMID: 18675497 (View on PubMed)

Bouwsema H, van der Sluis CK, Bongers RM. Movement characteristics of upper extremity prostheses during basic goal-directed tasks. Clin Biomech (Bristol). 2010 Jul;25(6):523-9. doi: 10.1016/j.clinbiomech.2010.02.011. Epub 2010 Apr 1.

Reference Type BACKGROUND
PMID: 20362374 (View on PubMed)

Loiret I, Paysant J, Martinet N, Andre JM. [Evaluation of amputees]. Ann Readapt Med Phys. 2005 Jul;48(6):307-16. doi: 10.1016/j.annrmp.2005.03.009. Epub 2005 Apr 15. French.

Reference Type BACKGROUND
PMID: 15932782 (View on PubMed)

Demers L, Weiss-Lambrou R, Ska B. Development of the Quebec User Evaluation of Satisfaction with assistive Technology (QUEST). Assist Technol. 1996;8(1):3-13. doi: 10.1080/10400435.1996.10132268.

Reference Type BACKGROUND
PMID: 10159726 (View on PubMed)

Miller LA, Stubblefield KA, Lipschutz RD, Lock BA, Kuiken TA. Improved myoelectric prosthesis control using targeted reinnervation surgery: a case series. IEEE Trans Neural Syst Rehabil Eng. 2008 Feb;16(1):46-50. doi: 10.1109/TNSRE.2007.911817.

Reference Type BACKGROUND
PMID: 18303805 (View on PubMed)

Gouzien A, de Vignemont F, Touillet A, Martinet N, De Graaf J, Jarrasse N, Roby-Brami A. Reachability and the sense of embodiment in amputees using prostheses. Sci Rep. 2017 Jul 10;7(1):4999. doi: 10.1038/s41598-017-05094-6.

Reference Type BACKGROUND
PMID: 28694439 (View on PubMed)

Other Identifiers

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2016-A00897-44

Identifier Type: OTHER

Identifier Source: secondary_id

20PT003-FR-01-0516

Identifier Type: -

Identifier Source: org_study_id

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