Novel Point-of-Care Diagnostic Test for SARS-CoV-2 (COVID-19)

NCT ID: NCT04513990

Last Updated: 2021-12-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

257 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-04-09

Study Completion Date

2023-04-30

Brief Summary

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This study investigates a new diagnostic test in detecting SARS-CoV-2, the virus that causes the disease COVID-19. This may help to improve testing for COVID-19.

Detailed Description

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PRIMARY OBJECTIVE:

I. To evaluate the clinical performance of a novel point-of-care diagnostic test for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the disease called coronavirus disease 19 (COVID-19).

SECONDARY OBJECTIVES:

I. To compare the clinical performance of provider-collected nasopharyngeal samples with self-collected nasal swab, cheek swab, and saliva sample using the novel SARS-CoV-2 diagnostic test.

II. To measure viral load and evaluate the role of viral load in COVID-19 severity.

OUTLINE:

Participants undergo collection of nasopharyngeal (back of the nose) samples by a medical provider and self-collection of oral, saliva, and nasal samples.

After completion of study, participants are followed up at 1 month.

Conditions

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COVID-19 Infection

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Diagnostic (biospecimen collection)

Participants undergo collection of nasopharyngeal (back of the nose) samples by a medical provider and self-collection of oral, saliva, and nasal samples.

Group Type EXPERIMENTAL

Biospecimen Collection

Intervention Type PROCEDURE

Undergo collection of nasopharyngeal, oral, saliva, and nasal samples

Questionnaire Administration

Intervention Type OTHER

Demographic information, sample collection type preferences; clinical outcome information

Interventions

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Biospecimen Collection

Undergo collection of nasopharyngeal, oral, saliva, and nasal samples

Intervention Type PROCEDURE

Questionnaire Administration

Demographic information, sample collection type preferences; clinical outcome information

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Qualifies for SARS-CoV-2 testing at MD Anderson, Lyndon B. Johnson (LBJ) hospital, or affiliated sites (may include MD Anderson and LBJ patients and employees) according to institutional criteria at time of enrollment
* Willing and able to provide informed consent
* Ability to perform protocol-required activities
* Able to speak and read English or Spanish

Exclusion Criteria

* Patient or provider decision not to perform SARS-CoV-2 testing
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

William Marsh Rice University

OTHER

Sponsor Role collaborator

M.D. Anderson Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kathleen M Schmeler

Role: PRINCIPAL_INVESTIGATOR

M.D. Anderson Cancer Center

Locations

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Lyndon Baines Johnson General Hospital

Houston, Texas, United States

Site Status

M D Anderson Cancer Center

Houston, Texas, United States

Site Status

Countries

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United States

Related Links

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http://www.mdanderson.org

MD Anderson Cancer Center Website

Other Identifiers

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NCI-2020-03470

Identifier Type: REGISTRY

Identifier Source: secondary_id

2020-0318

Identifier Type: OTHER

Identifier Source: secondary_id

2020-0318

Identifier Type: -

Identifier Source: org_study_id