Investigation of Novel Immunological Biomarkers by Mass Cytometry in Patients With Early Multiple Sclerosis (CISCO)

NCT ID: NCT04510350

Last Updated: 2022-03-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-02-19

Study Completion Date

2022-03-02

Brief Summary

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The objective of CISCO is therefore to identify prognostic biomarkers of MS activity in early-stage patients.

Detailed Description

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Conditions

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Multiple Sclerosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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MS CIS+

Biomarkers analysis

Intervention Type OTHER

Genetic analysis of regions of interest

Healthy volunteers

Biomarkers analysis

Intervention Type OTHER

Genetic analysis of regions of interest

Interventions

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Biomarkers analysis

Genetic analysis of regions of interest

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with clinically isolated syndrome (CIS) participating in the OFSEP cohort (French MS Observatory)
* At least 18 years of age
* Diagnosed with MS according to criteria 2017 at the time of their last visit.
* Non-opposition to participation in the study
* Having had at least one visit in the year following collection
* Follow-up for at least 1 year after collection.
* Having signed the OFSEP consent


* Age 18 years or older
* Having participated in the ABCD-SEP clinical trial promoted by the Rennes University Hospital (NCT03744351).
* Matched on age and sex to patients of interest in the OFSEP cohort
* Not having objected to participation in the study

Exclusion Criteria

* CIS patients with progressive MS

Healthy volunteers :


* Persons of full age subject to legal protection (safeguard of justice, curatorship, guardianship), persons deprived of liberty
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Rennes University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Laure Michel, Md

Role: PRINCIPAL_INVESTIGATOR

Rennes University Hospital

Locations

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CHU Rennes

Rennes, , France

Site Status

Countries

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France

Other Identifiers

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35RC19_8880_CISCO

Identifier Type: -

Identifier Source: org_study_id

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