Efficiency and Safety of High-frequency Radio Wave Electrotherapy With a Radio Frequency of 448 kHz in the Treatment of Patients With Organic Erectile Dysfunction.

NCT ID: NCT04506658

Last Updated: 2021-07-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-06-01

Study Completion Date

2021-12-31

Brief Summary

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Efficiency and safety of high-frequency radio wave electrotherapy with a radio frequency of 448 kHz in the treatment of patients with organic erectile dysfunction. Sham comparator, parallel study including both the main and control group to demonstrate the efficiency of the device to treat erectile dysfunction.

Detailed Description

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The objectives of this study are:

* To evaluate the effectiveness of the course treatment with the apparatus for continuous capacitive resistive monopolar electrotherapy with a radio frequency of 448 kHz in patients with organic erectile dysfunction.
* Assess the safety and tolerability of continuous capacitive resistive monopolar electrotherapy with a radio frequency of 448 kHz in patients with organic erectile dysfunction.
* To evaluate the duration of the effect of continuous capacitive resistive monopolar electrotherapy with a radio frequency of 448 kHz.

Conditions

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Erectile Dysfunction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Intervention group

Group Type EXPERIMENTAL

high-frequency radio wave electrotherapy with a frequency of 448 kHz on the penis structures.

Intervention Type DEVICE

Patient in lithotomy position (supine) with return plate at lumbar level.

Start with high power (within the allowed range) to get a faster hyperthermia and slowly decrease this percentage as the current builds up in the patient's body.

Patients are undergoing high-frequency radio wave electrotherapy 2 times a week (12 procedures at all).

Control group

Group Type SHAM_COMPARATOR

high-frequency radio wave electrotherapy with a frequency of 448 kHz on the penis structures.

Intervention Type DEVICE

Doctor uses sham sensor to reduce efficiency to zero.

Interventions

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high-frequency radio wave electrotherapy with a frequency of 448 kHz on the penis structures.

Patient in lithotomy position (supine) with return plate at lumbar level.

Start with high power (within the allowed range) to get a faster hyperthermia and slowly decrease this percentage as the current builds up in the patient's body.

Patients are undergoing high-frequency radio wave electrotherapy 2 times a week (12 procedures at all).

Intervention Type DEVICE

high-frequency radio wave electrotherapy with a frequency of 448 kHz on the penis structures.

Doctor uses sham sensor to reduce efficiency to zero.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Patients aged 18 to 79 years;
2. The diagnosis is confirmed by assessing the functional criteria of arterial factors of panel hemodynamics (dopplerography);
3. The diagnosis is confirmed by the assessment of the IIEF-5 questionnaire
4. Patients with organic erectile dysfunction lasting at least 6 months.
5. Patients with IIEF from 6 to 22 points.
6. Patients with a permanent sexual partner for more than 3 months;
7. Sexually Active Patients.


1. The use of other treatments for erectile dysfunction
2. Age under 18 and over 79 years old;
3. Anatomical deformation of the penis (angulation, cavernous fibrosis or Peyronie's disease);
4. The presence of diseases predisposing to the development of priapism (sickle cell anemia, multiple myeloma, leukemia, thrombocytopenia);
5. Running coagulation disorders;
6. The presence of tumors in the area of electrotherapy;
7. The presence of aneurysms in the propagation of radio frequency waves;
8. Angina pectoris;
9. Myocardial infarction, stroke, life-threatening arrhythmias;
10. Thrombosis, thromboembolic disease;
11. Arterial hypertension (blood pressure ≥ 170/90 mm Hg) or hypotension (blood pressure ≤ 90/50 mm Hg.);
12. The patient has a mental illness that does not allow an assessment of the effectiveness of therapy; history of alcoholism and drug addiction;

14\. Active tuberculosis, chronic somatic diseases in the acute stage; 15. Condition after coronary artery bypass grafting (CABG); 16. Patient's involvement in another clinical trial in the last 3 months;

5. Serious deviation from the protocol.
6. The desire of the patient or his legal representative.

Exclusion Criteria

1. Serious unwanted phenomenons associated with exposure to the apparatus.
2. Incorrect inclusion in the study.
3. A marked deterioration in the patient's condition due to an increase in the severity of the disease or the attachment of another disease.
Minimum Eligible Age

18 Years

Maximum Eligible Age

79 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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I.M. Sechenov First Moscow State Medical University

OTHER

Sponsor Role lead

Responsible Party

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Dmitry Enikeev, MD, PhD

Director for Research

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Dmitry Korolev, M.D.

Role: PRINCIPAL_INVESTIGATOR

Sechenov University

Locations

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Institute for Urology and Reproductive Health, Sechenov University.

Moscow, , Russia

Site Status RECRUITING

Countries

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Russia

Central Contacts

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Dmitry Enikeev, M.D., Ph.D.

Role: CONTACT

89267677873

Dmitry Korolev, M.D.

Role: CONTACT

89267677873

Facility Contacts

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Dmitry Enikeev, M.D., Ph.D

Role: primary

+79267677873

Dmitry Korolev, MD

Role: backup

+79267677873

Related Links

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Other Identifiers

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07-20 from 15.04.2020

Identifier Type: -

Identifier Source: org_study_id

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