Oral Cancer Screening and Education in Hong Kong

NCT ID: NCT04487938

Last Updated: 2020-07-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

3190 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-08-01

Study Completion Date

2024-07-31

Brief Summary

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This study will be conducted to obtain data on oral cancer risk factors to generate machine learning models with good predictive accuracy for stratifying individuals with high-oral cancer risk and delineating high-risk and low-risk oral lesions. Likewise, this study will seek to provide oral cancer-related health education and training on oral-self-examination for beneficiaries

Detailed Description

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Conditions

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Oral Cancer Oral Leukoplakia Oral Submucous Fibrosis Proliferative Verrucous Leukoplakia Oral Erythroplakia Erosive Lichen Planus

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Tobacco use and/or alcohol consumption

No intervention utilised

Intervention Type OTHER

No intervention utilised

No tobacco use and/or alcohol consumption

No intervention utilised

Intervention Type OTHER

No intervention utilised

Interventions

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No intervention utilised

No intervention utilised

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy individuals satisfying age and residential area criteria with no previous history of oral cancer. Individuals with a history of other cancers will be included in the study provided they have been in remission for more than three years.

Exclusion Criteria

* Participants with reduced mouth opening (irrespective of the cause) to permit proper administration of VOE or photosensitive epilepsy will be excluded. Likewise, those who decline the provision of written consent or participation in any part of the study.
Minimum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Professor Peter James Thomson

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Peter Thomson

Role: PRINCIPAL_INVESTIGATOR

The University of Hong Kong

Central Contacts

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John Adeoye

Role: CONTACT

References

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Adeoye J, Choi SW, Thomson P. Bayesian disease mapping and the 'High-Risk' oral cancer population in Hong Kong. J Oral Pathol Med. 2020 Oct;49(9):907-913. doi: 10.1111/jop.13045. Epub 2020 Jun 10.

Reference Type BACKGROUND
PMID: 32450000 (View on PubMed)

Adeoye J, Brennan PA, Thomson P. "Search less, verify more"-Reviewing salivary biomarkers in oral cancer detection. J Oral Pathol Med. 2020 Sep;49(8):711-719. doi: 10.1111/jop.13003. Epub 2020 Mar 5.

Reference Type BACKGROUND
PMID: 32027406 (View on PubMed)

Adeoye J, Chu CS, Choi SW, Thomson P. Oral Cancer Awareness and Individuals' Inclination to Its Screening and Risk Prediction in Hong Kong. J Cancer Educ. 2022 Apr;37(2):439-448. doi: 10.1007/s13187-020-01834-x.

Reference Type BACKGROUND
PMID: 32705524 (View on PubMed)

Adeoye J, Thomson P. Strategies to improve diagnosis and risk assessment for oral cancer patients. Faculty Dental Journal. 2020;11(3):122-7.

Reference Type BACKGROUND

Other Identifiers

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[email protected]

Identifier Type: -

Identifier Source: org_study_id

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