A Smart Self-Management Support Programme (3S) to Improve Quality of Life in Lung Cancer Patients

NCT ID: NCT06377124

Last Updated: 2025-03-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

320 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-04-22

Study Completion Date

2026-06-30

Brief Summary

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Lung cancers patients often experience multiple symptoms (e.g. fatigue, dyspnea, distress, depression, sleep disturbance). The current study attempts to explore the efficacy of the Smart Self-Management Support Programme (3S) in improving quality of life of patients using self-management support programme with mobile devices.

Detailed Description

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Lung cancer (LC) is the most and second most common cancer globally and locally respectively. LC patients often experience multiple symptoms (e.g. fatigue, dyspnea, distress, depression, sleep disturbance). The symptom burden is greater than other cancers and adversely affects quality of life. Care of LC patients has shifted from a purely disease-centered approach on survival-related outcomes to person-centered approach with emphasis on quality-of-life outcomes.

Self-management support programme (SMS) is perceived to supplement regular medical treatments and follow-up and cost-effective in cancer care. Besides, digital technologies have been used in patient empowerment digital platform to improve self-management of cancer patients. Using the self-management support programme and mobile devices, the Smart Self-Management Support Programme (3S) attempts to improve quality of life of patients.

The current study aims to examine the efficacy of 3S on improving quality of life and patient activation (knowledge, skills, and confidence for self-management) in the 3S intervention group, compared to the general health (GH) control group. It also aims to examine the changes in the burden of care, anxiety and depression symptoms, and quality of life of the family caregivers (FCGs) of the patients in the 3S group, compared to FCGs of the patients in the GH group.

We also conduct process valuations to assess the essential features of context, implementation, and impact mechanism, and cost-effectiveness evaluation to examine health care resource utilisation and cost-effectiveness analysis.

160 patients with lung cancer will be recruited, and 160 family caregivers will also be invited to join the study.

Conditions

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Lung Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

The 3S intervention includes an individual session, messaging and phone contact related to lung cancer self-management, and hotline services.

The general health information includes an individual session, messaging and phone contact related to general health information, and hotline services.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Outcome Assessors
The outcome assessor was not aware of which groups the patients belonged to.

Study Groups

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The 3S intervention group

Receive information and support on self-management of lung cancer

Group Type EXPERIMENTAL

3S intervention

Intervention Type BEHAVIORAL

The 3S intervention includes information and support related to self-management of lung cancer, including

1. an individual 3S session at baseline,
2. 24-week messaging, telephone coaching and hotline services.

The GH information group

Receive general health information such as sleep hygiene, environmental hygiene, etc.

Group Type PLACEBO_COMPARATOR

GH information

Intervention Type BEHAVIORAL

The GH information includes information related to general health, including

1. an individual GH session at baseline,
2. 24-week messaging, telephone coaching and hotline services.

Interventions

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3S intervention

The 3S intervention includes information and support related to self-management of lung cancer, including

1. an individual 3S session at baseline,
2. 24-week messaging, telephone coaching and hotline services.

Intervention Type BEHAVIORAL

GH information

The GH information includes information related to general health, including

1. an individual GH session at baseline,
2. 24-week messaging, telephone coaching and hotline services.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Aged 18 years or above
* Diagnosis of advanced-stage (stage III or stage IV) non-small cell lung cancer
* Ambulatory and capable of all self-care activities (ECOG ≤2)
* Either undergoing or has finished oncology therapy
* Mentally, cognitively and physically fit to join as determined by the doctor in charge and responsible clinical investigators
* Can speak and read Chinese
* Willing to complete the patient-reported outcome questionnaire
* Has a smartphone with WhatsApp or WeChat


* Aged 18 years or above
* Family caregivers of recruited patients

Exclusion Criteria

* Preparing for lung operation
* Skeletal fragility
* Serious active infection
* Inability to walk
* Previously untreated symptomatic brain metastases
* Severe respiratory insufficiency
* Uncontrolled pain
* Diagnosed psychiatric illness with or without medication

Family Caregivers:


* Unable to speak and read Chinese
* Unwilling to complete the patient-reported outcome questionnaire
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Queen Mary Hospital, Hong Kong

OTHER

Sponsor Role collaborator

The Queen Elizabeth Hospital

OTHER

Sponsor Role collaborator

United Christian Hospital

OTHER

Sponsor Role collaborator

The University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Dr. Agnes Yuen-Kwan Lai

Honorary Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Agnes Yuen Kwan Lai, PhD

Role: PRINCIPAL_INVESTIGATOR

School of Nursing and Health Sciences

Locations

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Queen Elizabeth Hospital

Hong Kong, Ho ManTin, Hong Kong

Site Status RECRUITING

Queen Mary Hospital

Hong Kong, , Hong Kong

Site Status NOT_YET_RECRUITING

United Christian Hospital

Hong Kong, , Hong Kong

Site Status RECRUITING

Countries

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Hong Kong

Central Contacts

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Agnes Yuen Kwan Lai, PhD

Role: CONTACT

852 3970 2917

Facility Contacts

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Maggie Lit, MN

Role: primary

(852) 39702917

Role: backup

Agnes YK Lai, PhD

Role: primary

3970-2903

Shu wah Ng, MSc

Role: primary

References

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Kondylakis H, Bucur A, Crico C, Dong F, Graf N, Hoffman S, Koumakis L, Manenti A, Marias K, Mazzocco K, Pravettoni G, Renzi C, Schera F, Triberti S, Tsiknakis M, Kiefer S. Patient empowerment for cancer patients through a novel ICT infrastructure. J Biomed Inform. 2020 Jan;101:103342. doi: 10.1016/j.jbi.2019.103342. Epub 2019 Dec 6.

Reference Type BACKGROUND
PMID: 31816400 (View on PubMed)

Saetan P, Chaiviboontham S, Pokpalagon P, Chansriwong P. The Effects of the Respiratory Rehabilitation Program on Perceived Self-Efficacy and Dyspnea in Patients with Lung Cancer. Asian Nurs Res (Korean Soc Nurs Sci). 2020 Dec;14(5):277-285. doi: 10.1016/j.anr.2020.08.010. Epub 2020 Sep 8.

Reference Type BACKGROUND
PMID: 32916339 (View on PubMed)

Zhu X, Han S, Chu H, Wang M, Chen S. Influence of self-management exercise intervention on the cancer related fatigue severity and self-management efficacy of patients with non-small cell lung cancer after operation. J Pak Med Assoc. 2020 Sep;70 [Special Issue](9):88-93.

Reference Type BACKGROUND
PMID: 33177734 (View on PubMed)

Hernandez Silva E, Lawler S, Langbecker D. The effectiveness of mHealth for self-management in improving pain, psychological distress, fatigue, and sleep in cancer survivors: a systematic review. J Cancer Surviv. 2019 Feb;13(1):97-107. doi: 10.1007/s11764-018-0730-8. Epub 2019 Jan 11.

Reference Type BACKGROUND
PMID: 30635865 (View on PubMed)

Ji W, Kwon H, Lee S, Kim S, Hong JS, Park YR, Kim HR, Lee JC, Jung EJ, Kim D, Choi CM. Mobile Health Management Platform-Based Pulmonary Rehabilitation for Patients With Non-Small Cell Lung Cancer: Prospective Clinical Trial. JMIR Mhealth Uhealth. 2019 Jun 21;7(6):e12645. doi: 10.2196/12645.

Reference Type BACKGROUND
PMID: 31228180 (View on PubMed)

Other Identifiers

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UW21-507

Identifier Type: -

Identifier Source: org_study_id

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