Nasopharyngeal Carcinoma Screening in Zhongshan City

NCT ID: NCT02501993

Last Updated: 2023-07-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

25000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-03-31

Study Completion Date

2023-12-31

Brief Summary

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The primary objective is to determine the early diagnosis rate and mortality rate of the Nasopharyngeal Carcinoma (NPC) in the study population.

The secondary objective is to determine the incidence of NPC in the study population.

Detailed Description

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The research is to evaluate the effect of NPC screening, also as an extended study of Screening for Nasopharyngeal Carcinoma in High Risk Populations (NCT00941538).

The program was conducted in Xiaolan and Minzhong towns of Zhongshan city in 2012.

All participants will be tested for anti-EBV antibody by using serum samples. Participants are stratified into those having high, moderate and low antibody levels, those having moderate antibody levels are invited to retest annually in the following 3 years and those found to have high antibody levels on these occasions are referred to centers for diagnostic workup for NPC.

Conditions

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Nasopharyngeal Carcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Screening cohort

All participants will be tested for anti-EBV antibody by using serum samples. Participants are stratified into those having high, moderate and low antibody levels, those having moderate antibody levels are invited to retest annually in the following 3 years and those found to have high antibody levels on these occasions are referred to centers for diagnostic workup for NPC.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Subject residents in Zhongshan city
* Subject is 30 to 59 years of age inclusive
* Subject has no medical record of nasopharyngeal carcinoma
* ECOG 0-2
* Subject has psychical condition and well consciousness
* Subject is able to comprehend, sign, and date the written informed consent document to participate in the study.

Exclusion Criteria

* Subject has heavy cardiovascular, liver or kidney disease
* Subject has medical record of nasopharyngeal carcinoma
* Subject who is not residing in Zhongshan City
Minimum Eligible Age

30 Years

Maximum Eligible Age

59 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Zhongshan People's Hospital, Guangdong, China

OTHER

Sponsor Role lead

Responsible Party

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Mingfang Ji

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mingfang Ji, MD

Role: PRINCIPAL_INVESTIGATOR

Zhongshan People's Hospital, Guangdong, China

Locations

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Zhongshan People's Hospital

Zhongshan, Guangdong, China

Site Status

Countries

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China

Other Identifiers

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NPC-PRO-002

Identifier Type: -

Identifier Source: org_study_id

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