Assessment of the Effects of Extensive Somatosensory Training on Pain Processing
NCT ID: NCT04457466
Last Updated: 2022-03-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
100 participants
OBSERVATIONAL
2017-10-01
2020-07-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Healthy musicians
Men and women aged 18-60, who must be enrolled in a music conservatory performance program or be professionally active, and must speak and understand English.
Nerve Growth Factor
Induction of experimental muscle soreness using intramuscular injections of Nerve Growth Factor.
Healthy non-musicians
Men and women aged 18-60, must speak and understand English and not have any kind of musical training.
Nerve Growth Factor
Induction of experimental muscle soreness using intramuscular injections of Nerve Growth Factor.
Musicians with chronic pain
Men and women aged 18-60 with chronic and idiopathic musculoskeletal upper limb and/or neck pain lasting more than 6 months. They must be enrolled in a music conservatory performance program or be professionally active and must speak and understand English.
Nerve Growth Factor
Induction of experimental muscle soreness using intramuscular injections of Nerve Growth Factor.
Non-musicians with chronic pain
Men and women aged 18-60 with chronic and idiopathic musculoskeletal upper limb and/or neck pain lasting more than 6 months. They must not have any kind of musical training and must speak and understand English.
Nerve Growth Factor
Induction of experimental muscle soreness using intramuscular injections of Nerve Growth Factor.
Interventions
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Nerve Growth Factor
Induction of experimental muscle soreness using intramuscular injections of Nerve Growth Factor.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Drug addiction defined as the use of cannabis, opioids or other drugs
* Previous neurologic or mental illnesses
* Presence of a history of trauma or neurologic entrapment syndromes to the arm regions.
* Lack of ability to cooperate
* Frequent computer gamer ( \> 9 hours/week)
18 Years
60 Years
ALL
Yes
Sponsors
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University of Aarhus
OTHER
Lundbeck Foundation
OTHER
Danish National Research Foundation
OTHER
Aalborg University
OTHER
Responsible Party
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Anna M. Zamorano
Principal Investigator
Locations
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Aalborg University
Aalborg, North Denmark, Denmark
Countries
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References
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Zamorano AM, Kleber B, De Martino E, Insausti-Delgado A, Vuust P, Flor H, Graven-Nielsen T. Prior use-dependent plasticity triggers different individual corticomotor responses during persistent musculoskeletal pain. Pain. 2025 Jul 30. doi: 10.1097/j.pain.0000000000003749. Online ahead of print.
Other Identifiers
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10042017
Identifier Type: -
Identifier Source: org_study_id
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