Muscle Stretching - the Potential Role of Endogenous Pain Inhibitory Modulation on Stretch Tolerance

NCT ID: NCT03713788

Last Updated: 2018-10-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-05-01

Study Completion Date

2016-11-30

Brief Summary

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This study investigates the influence of a remote, painful stimulus on stretch tolerance. Half of the participants will receive a conditioning painful stimulus following static stretching while the other half will rest quietly.

Detailed Description

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The effect of stretching on joint range of motion is primarily related to changes in the tolerance to stretch, but the mechanisms underlying this change are still largely unknown.

The nervous system has an inbuilt ability to modulate the perceived magnitude of afferent noxious stimuli via supraspinally mediated endogenous pain inhibition or facilitation and by engaging endogenous mechanisms pain tolerance in healthy individuals is known to increase. Thus increasing the tolerance to pain could potentially increase range of motion following stretching.

Conditions

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Muscle Stretching Exercises Pain Threshold

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

A sample of convenience was recruited for this cross-sectional study. Participants were randomly assigned to a pain group or a control group using counterbalanced block randomization. Passive knee extension range of motion was measured three consecutive times with five-minute intervals between measurements. Both groups underwent a static stretch protocol consisting of two bouts of thirty-second constant-angle static stretching of the knee flexors with a one-minute rest between bouts. Subjects were instructed to keep the limb relaxed as the lower leg was passively moved towards extension. Following stretching, the post-stretch measurement was performed. Finally, subjects in the pain group were instructed to immerse their non-dominant hand into a container with circulating water at 1˚C to 4˚C and keep it there for 2 minutes. A Biodex system 4 pro dynamometer was used to quantify range of motion and passive resistive torque. Muscle activity was recorded as surface electromyography.
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Experimental pain group

subjects in the pain group were instructed to immerse their non-dominant hand into a container with circulating water at 1˚C to 4˚C and keep it there for 2 minutes. They were instructed to immerse it to wrist-level and keep the hand open.

Group Type EXPERIMENTAL

Cold pressor test

Intervention Type OTHER

Participants placed their non-dominant hand into cold water for 2 minutes

Control group

Participants rested in a seated position for 5 minutes.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Cold pressor test

Participants placed their non-dominant hand into cold water for 2 minutes

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Eligibility for participation included the absence of any pain or other conditions that might affect the somatosensory system.

Exclusion Criteria

* Substance abuse,
* History of neurological or mental disabilities
* Lack of ability to comply with instructions
* Delayed onset of muscle soreness.
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Aalborg University

OTHER

Sponsor Role collaborator

University College of Northern Denmark

OTHER

Sponsor Role lead

Responsible Party

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Morten Pallisgaard

Senior associate lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Dorte Drachman, Msc.

Role: STUDY_DIRECTOR

University College of Northern Denmark, Department of Physiotherapy

Locations

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University College of Northern Denmark

Aalborg, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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UniversityCND

Identifier Type: -

Identifier Source: org_study_id

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