Combined Endophthalmitis and Orbital Cellulitis in Patients With Novel Coronavirus Disease (COVID-19)

NCT ID: NCT04456556

Last Updated: 2020-07-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

5 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-27

Study Completion Date

2020-06-30

Brief Summary

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To report on cases presented with combined endophthalmitis and orbital cellulitis as a first presentation of covid-19 infection.

Detailed Description

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This observation case series study included 5 patients referred to the Ophthalmology Department, Minia University with severe ophthalmic manifestations in the form of combined endophthalmitis and orbital cellulitis. On doing the work-up of covid-19 infection according to the recommendations of Egyptian Ministry of Health, patients proved to be infected by the novel Corona virus. In addition to the Corona work-up, all patients were subjected to full ophthalmological evaluation, ocular ultrasound and orbital CT examination.

Conditions

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Endophthalmitis and Orbital Cellulitis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients with endophthalmitis and orbital cellulitis with covid-19

Exclusion Criteria

* Patients without endophthalmitis and orbital cellulitis.
* Patients with endophthalmitis and orbital cellulitis not having covid-19 infection.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Minia University

OTHER

Sponsor Role lead

Responsible Party

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Mohamed Farouk Sayed Othman Abelkader

associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Minia university Hospital

Minya, Minya Governorate, Egypt

Site Status

Countries

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Egypt

References

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Chen L, Liu M, Zhang Z, Qiao K, Huang T, Chen M, Xin N, Huang Z, Liu L, Zhang G, Wang J. Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease. Br J Ophthalmol. 2020 Jun;104(6):748-751. doi: 10.1136/bjophthalmol-2020-316304. Epub 2020 Apr 7.

Reference Type BACKGROUND
PMID: 32265202 (View on PubMed)

Turbin RE, Wawrzusin PJ, Sakla NM, Traba CM, Wong KG, Mirani N, Eloy JA, Nimchinsky EA. Orbital cellulitis, sinusitis and intracranial abnormalities in two adolescents with COVID-19. Orbit. 2020 Aug;39(4):305-310. doi: 10.1080/01676830.2020.1768560. Epub 2020 May 18.

Reference Type BACKGROUND
PMID: 32419568 (View on PubMed)

Elshafei AMK, Sayed MF, Abdallah RMA. Clinical profile and outcomes of management of orbital cellulitis in Upper Egypt. J Ophthalmic Inflamm Infect. 2017 Dec;7(1):8. doi: 10.1186/s12348-017-0126-3. Epub 2017 Mar 9.

Reference Type BACKGROUND
PMID: 28275981 (View on PubMed)

Abdelkader MFSO, Elshafei AMK, Nassar MM, Abu Elela MA, Abdallah RMA. Combined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19). J Ophthalmic Inflamm Infect. 2021 Sep 15;11(1):27. doi: 10.1186/s12348-021-00258-y.

Reference Type DERIVED
PMID: 34523045 (View on PubMed)

Other Identifiers

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ocular infection in covid19

Identifier Type: -

Identifier Source: org_study_id

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