Protective Effect of CoQ10 Against Negative Inflammatory Response and Organ Dysfunction in Cardiovascular Surgery (PANDA V)
NCT ID: NCT04444349
Last Updated: 2024-11-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
500 participants
INTERVENTIONAL
2021-02-01
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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Coenzyme Q10 group
Participants in the experimental group will be given 10mg of Coenzyme Q10 each time (3 times a day).
Coenzyme Q10
Coenzyme Q10 is a cardiovascular health supplement. It is a component of the electron transport chain and participates in aerobic cellular respiration, which generates energy in the form of ATP. The ingredients in Coenzyme Q10 help regulate the body's production of free radicals, strengthen the arteries and heart, and reverse oxidation.
Control
patients only receive standard medical therapy.
Standard Medical Therapy
Patients only received standard medical therapy without CoQ10.
Interventions
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Coenzyme Q10
Coenzyme Q10 is a cardiovascular health supplement. It is a component of the electron transport chain and participates in aerobic cellular respiration, which generates energy in the form of ATP. The ingredients in Coenzyme Q10 help regulate the body's production of free radicals, strengthen the arteries and heart, and reverse oxidation.
Standard Medical Therapy
Patients only received standard medical therapy without CoQ10.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Who receive cardiovascular surgery
* Agree to participate in the surgery and sign the informed consent form
Exclusion Criteria
* Contain a minimum of 2 traits of metabolic syndrome
* Refused to participate in the surgery and refused informed consent
18 Years
90 Years
ALL
No
Sponsors
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The First Affiliated Hospital with Nanjing Medical University
OTHER
Beijing Anzhen Hospital
OTHER
West China Hospital
OTHER
The First Affiliated Hospital of Guangzhou Medical University
OTHER
Nanjing Medical University
OTHER
Responsible Party
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Hong Liu
Investigator of Cardio-Thoracic Surgery
Locations
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Beijing Anzhen Hospital
Beijing, Beijing Municipality, China
The First Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China
The First Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China
West China Hospital of Sichuan University
Chengdu, Sichuan, China
Countries
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Central Contacts
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Facility Contacts
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Si-chong Qian
Role: backup
Ying-yuan Zhang, MD
Role: backup
Hong Liu, MD
Role: backup
Hong-hua Yue, MD
Role: backup
Other Identifiers
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PANDA V
Identifier Type: -
Identifier Source: org_study_id
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