Neurodevelopment at 5.5 Years of Age in Children Who Received Infant Formula With Enriched Protein Fractions

NCT ID: NCT04442477

Last Updated: 2021-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

116 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-15

Study Completion Date

2021-05-27

Brief Summary

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This is a follow-up study of a multi-center, double-blind, randomized, controlled, parallel-designed, prospective trial and is intended to evaluate neurodevelopment at 5.5 years of age and health outcomes through 5.5 years of age in participants who received one of two staged study formulas through one year of age.

Detailed Description

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Conditions

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Cognitive Ability, General

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Experimental: Enriched Protein Fractions

This group was given Infant formula with enriched protein fractions

Enriched Protein Fractions

Intervention Type DIETARY_SUPPLEMENT

Enriched protein fractions

Active Comparator: Protein Fractions

This group was given Infant formula with protein fractions

Protein Fraction

Intervention Type DIETARY_SUPPLEMENT

Protein fractions

Interventions

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Enriched Protein Fractions

Enriched protein fractions

Intervention Type DIETARY_SUPPLEMENT

Protein Fraction

Protein fractions

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Participant who previously consumed study formula through one year of age in MJN Project 6027
* 5.5 years of age (i.e. when child turns 5 years and 6 months old ± 2 months) at Visit 1
* Signed informed consent obtained for child's participation in the study
Minimum Eligible Age

64 Months

Maximum Eligible Age

68 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mead Johnson Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Fei Li

Role: PRINCIPAL_INVESTIGATOR

Shanghai Children's Medical Center

Steven Wu, M.D.

Role: STUDY_DIRECTOR

Mead Johnson/RB

Locations

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Fuyang Fifth People's Hospital

Anhui, , China

Site Status

Countries

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China

References

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Colombo J, Harris CL, Wampler JL, Zhuang W, Shaddy DJ, Liu BY, Wu SS. Improved Neurodevelopmental Outcomes at 5.5 Years of Age in Children Who Received Bovine Milk Fat Globule Membrane and Lactoferrin in Infant Formula Through 12 Months: A Randomized Controlled Trial. J Pediatr. 2023 Oct;261:113483. doi: 10.1016/j.jpeds.2023.113483. Epub 2023 May 14.

Reference Type DERIVED
PMID: 37192722 (View on PubMed)

Other Identifiers

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6027-2

Identifier Type: -

Identifier Source: org_study_id