Home
Clinical Trials
Impact of Sleeve Gastrectomy ...

Impact of Sleeve Gastrectomy on Monocyte-to-High-Density Lipoprotein Cholesterol Ratio

Last Updated: 2020-06-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

125 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-01

Study Completion Date

2017-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The present study hypothesized that significant weight loss is associated with a reduction in the inflammatory markers, leading to diminished cardiovascular risks in patients undergoing laparoscopic sleeve gastrectomy (LGS).

We found a decrease in MHR at postoperative 6 months from baseline in patients undergoing LSG. The decrease in MHR was more remarkable with increasing percentage of EWL, but no relationship between the %EWL and MHR.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

the Change in Carotid Intima-media Thickness After Laparoscopic Sleeve Gastrectomy

NCT06882616

Weight Loss Reduce the Risk of Cardiac Disease Carotis Intima-media Thickness

COMPLETED NA

Effect of Clips Versus Omentopexy on Postoperative Bleeding

NCT06211699

Bleeding Postoperative Complications Postoperative Nausea and Vomiting

COMPLETED NA

Outcomes of Laparoscopic Sleeve Gastrectomy

NCT03983122

Bariatric Surgery Candidate Laparoscopic Sleeve Gastrectomy Obesity, Morbid

COMPLETED NA

Istmin Levels in Laparoscopik Sleeve Gastrectomy

NCT07335549

Obesity & Overweight Sleeve Gastrectomy Adipokines

COMPLETED

8-Year Outcomes After Sleeve Gastrectomy

NCT07348822

Sleeve Gastrectomy Obesity & Overweight

ACTIVE_NOT_RECRUITING

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The present study aims to evaluate the relationship between MHR, metabolic parameters and the percentage of excess weight loss (%EWL) in participants undergoing laparoscopic sleeve gastrectomy (LSG).

This prospective cohort study will evaluate obese participants undergoing LSG. Demographic data of the participants and blood glucose level, monocyte count and lipid parameters baseline and at 6 months after surgery will record. The MHR baseline and at 6 months after surgery and the %EWL at 6 months after surgery will calculate. The participants will be divide into two groups as participants with %EWL of \<50 and patients with a %EWL of ≥50. The parameters will compare between the two groups.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Laparoscopic Sleeve Gastrectomy Cardiovascular Risk Factor Obesity

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

Obese patients (BMI ≥40 or \>35+ and accompanying DM, HT and hyperlipidemia) Underwent laparoscopic sleeve gastrectomy.

Exclusion Criteria

Receiving antihyperlipidemic therapy, Important complications that continue within 6 months after surgery (anastomotic leaks, pulmonary embolism, deep vein thrombosis, soft tissue infection) Did not attend 6-month control visit were excluded from the study.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers