Operative Treatment of Ankle Fractures

NCT ID: NCT04437355

Last Updated: 2022-10-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-07-01

Study Completion Date

2021-12-31

Brief Summary

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Patients who underwent operative treatment of an ankle fracture with or without following removal of the osteosynthetic material are examined by a specific ankle provocation test, a questionnaire and X-Rays to evaluate the clinical, functional and radiological outcome compared to a healthy control group

Detailed Description

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The study includes all patients operated from 09.12.2012 to 31.12.2020. Patients will undergo an X-Ray at least two years after primary surgery or at least one year after removal of the osteosynthetic material. The patients operated from 09.12.2012 to date are therefore a retrospective cohort, the patients from to date until 31.12.2020 a prospective cohort. This method is used to achieve the highest possible number of patients in a define period of time with no alteration of surgical technique.

All patients in the retrospective cohort are contacted at least 2 years after surgery (or 1 year after removal) via phone call or letter, informed about the study and asked to participate. In case of informed consent, they are invited to the study site. They are asked to complete the questionnaires and they undergo X-Ray of the affected and the non-affected ankle.

All patients in the prospective cohort are informed about the study and asked to participate in the outpatient clinic. In case of informed consent, they are invited to the study site at least 2 years after surgery. They are asked to complete the questionnaires and they undergo na X-Ray of the affected and non-affected ankle.

Conditions

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Ankle Fracture, Trimalleolar Ankle Fracture - Lateral Malleolus Ankle Fracture, Bimalleolar

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Control Group

Young and healthy Group of People (18-50 years) without any pathology of the lower limb

Group Type ACTIVE_COMPARATOR

Specific provocation test

Intervention Type DIAGNOSTIC_TEST

To compare the results the investigators invite a healthy control group matching in age and gender with the intervention cohort. The control group is informed about the study and asked to participate in the outpatient clinic. In case of informed consent, the participants are invited to the study site. The participants undergo the same provocation test of the ankle, and are asked to complete the specific provocation test. In case of substantial underachievement in the provocation test (\<60% of maximum) an X-Ray of both ankles in a.p. and lateral projection is performed. The aim is to radiologically analyse the ankles, and to rule out any morphological reasons for the above mentioned underperformance.

Ankle Fracture Type Weber B

Young and healthy patients with an operative treated fracture of the ankle (type Weber B)

Group Type ACTIVE_COMPARATOR

Specific provocation test

Intervention Type DIAGNOSTIC_TEST

To compare the results the investigators invite a healthy control group matching in age and gender with the intervention cohort. The control group is informed about the study and asked to participate in the outpatient clinic. In case of informed consent, the participants are invited to the study site. The participants undergo the same provocation test of the ankle, and are asked to complete the specific provocation test. In case of substantial underachievement in the provocation test (\<60% of maximum) an X-Ray of both ankles in a.p. and lateral projection is performed. The aim is to radiologically analyse the ankles, and to rule out any morphological reasons for the above mentioned underperformance.

Ankle Fracture Weber C and complex

Young and healthy patients with an operative treated fracture of the ankle (type Weber C or complex fracture)

Group Type ACTIVE_COMPARATOR

Specific provocation test

Intervention Type DIAGNOSTIC_TEST

To compare the results the investigators invite a healthy control group matching in age and gender with the intervention cohort. The control group is informed about the study and asked to participate in the outpatient clinic. In case of informed consent, the participants are invited to the study site. The participants undergo the same provocation test of the ankle, and are asked to complete the specific provocation test. In case of substantial underachievement in the provocation test (\<60% of maximum) an X-Ray of both ankles in a.p. and lateral projection is performed. The aim is to radiologically analyse the ankles, and to rule out any morphological reasons for the above mentioned underperformance.

Interventions

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Specific provocation test

To compare the results the investigators invite a healthy control group matching in age and gender with the intervention cohort. The control group is informed about the study and asked to participate in the outpatient clinic. In case of informed consent, the participants are invited to the study site. The participants undergo the same provocation test of the ankle, and are asked to complete the specific provocation test. In case of substantial underachievement in the provocation test (\<60% of maximum) an X-Ray of both ankles in a.p. and lateral projection is performed. The aim is to radiologically analyse the ankles, and to rule out any morphological reasons for the above mentioned underperformance.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age older than 18 and younger than 51 years
* Operative treatment of an ankle fracture
* Time operation to follow up: at least 2 years
* Time removal of osteosynthetic material to follow up: at least 1 year
* Time operative treatment to removal of the osteosynthetic material: at least 9 months
* Informed Consent as documented by signature (Appendix: Informed Consent Form)

Exclusion Criteria

* Other pathologies of the lower limb of the affected and/or non-affected side (fractures, pre-existing arthrosis or operative treatment of the affected and/or non-affected limb)
* Pre-existing vascular (peripheral arterial disease, diabetes) or neurological diseases of the lower extremities
* Women who are pregnant
* Prevalence of an infection of the implanted osteosynthetic material
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Spital Limmattal Schlieren

OTHER

Sponsor Role lead

Responsible Party

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Prof Urs Zingg

Head of Department of surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Urs Zingg

Role: STUDY_CHAIR

Spital Limmattal Schlieren

Locations

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Spital Limmattal

Schlieren, Canton of Zurich, Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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2018-01124

Identifier Type: -

Identifier Source: org_study_id

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