Kinematic- Versus Ligament-balanced Mechanical Alignment in TKA

NCT ID: NCT04436211

Last Updated: 2020-06-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-02-15

Study Completion Date

2022-03-30

Brief Summary

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A promising new approach in total knee arthroplasty (TKA) for severe osteoarthritis of the knee joint is the the kinematic aligned procedure (KA). This technique provides prosthesis-positioning based on natural and individual axes of movement.

Although first series have shown satisfying results, further verification by prospective studies and final meta-analyses will be required.

Thus, the kinematic alignment represents one of the few new developments in TKA.

Provided that patients are willing to participate in the study, patients data are collected preoperatively and during routine follow-up examinations and evaluated prospectively. Patients will receive either a conventionally mechanical aligned arthroplasty or a kinematical aligned TKA, according to a randomized procedure.

The kinematic alignment will be achieved by the use of custom-made cutting-blocks. Therefore, the patients will undergo a computed tomography of the whole leg on the affected side. This is mandatory in order to provide the individually produced cutting blocks.

In order to ensure comparability, patients are stratified regarding their age and gender before inclusion.

Outcome will be measured by the use of standard scoring systems regarding function, pain and ROM (range of motion) three, six and 12 months after surgery.

This study is a monocentric, prospective, randomized and controlled open study.

Detailed Description

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Conditions

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Osteo Arthritis Knee

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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TKA (mechanical alignment)

Total Knee Arthroplasty

Intervention Type PROCEDURE

The common procedure of Total Knee Arthroplasty is investigated in order to compare the techniques of implantation (kinematic vs mechanical alignment)

TKA (kinematic alignment)

Total Knee Arthroplasty

Intervention Type PROCEDURE

The common procedure of Total Knee Arthroplasty is investigated in order to compare the techniques of implantation (kinematic vs mechanical alignment)

Interventions

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Total Knee Arthroplasty

The common procedure of Total Knee Arthroplasty is investigated in order to compare the techniques of implantation (kinematic vs mechanical alignment)

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\- Severe osteoarthritis of the knee joint, intended for total knee arthroplasty

Exclusion Criteria

\- malalignment with varus of more than 5° or valgus malpositioning, joint instability
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Medical University of Graz

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Medical University of Graz

Graz, , Austria

Site Status RECRUITING

Countries

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Austria

Central Contacts

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Patrick Sadoghi

Role: CONTACT

004331638580971

Ines Vielgut

Role: CONTACT

004331638581946

Facility Contacts

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Patrick Sadoghi

Role: primary

004361538580971

Other Identifiers

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032020

Identifier Type: -

Identifier Source: org_study_id

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