Repetitive Transcranial Magnetic Stimulation for the Treatment of Freezing of Gait in Parkinson's Disease
NCT ID: NCT04431570
Last Updated: 2020-06-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
66 participants
INTERVENTIONAL
2020-06-15
2022-06-14
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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rTMS over M1 region
The stimulus intensity was set to 100% of the resting motor threshold. Ten sessions of rTMS were delivered over 2 weeks, one session per day for 5 consecutive days per week. Each session consisted of 10 trains of 100 pulses at 10Hz with an inter-train interval of 40 seconds. In this group, the target of rTMS is M1 region.
rTMS
The device is made in London, United Kingdom
rTMS over supplementary motor area (SMA)
The stimulus intensity was set to 100% of the resting motor threshold. Ten sessions of rTMS were delivered over 2 weeks, one session per day for 5 consecutive days per week. Each session consisted of 10 trains of 100 pulses at 10Hz with an inter-train interval of 40 seconds. In this group, the target of rTMS is SMA region.
rTMS
The device is made in London, United Kingdom
sham stimulation
sham stimulation
the device of sham stimulation was MagStim MC-P-B70 placebo butterfly coil
Interventions
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rTMS
The device is made in London, United Kingdom
sham stimulation
the device of sham stimulation was MagStim MC-P-B70 placebo butterfly coil
Eligibility Criteria
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Inclusion Criteria
* Hoehn \& Yahr (H-Y) stage was 2 or 3
* All subjects had freezing of gait which was identified by FOGQ
Exclusion Criteria
* severe visual and/or haring impairment
* significant medical or psychiatric illnesses
* history of deep brain stimulation (DBS) surgery or pacemaker implantation. MRI cannot be performed in those patients
* current treatment with medication cannot be maintained during the study
50 Years
70 Years
ALL
No
Sponsors
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Peking Union Medical College Hospital
OTHER
Responsible Party
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Locations
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Peking Union Medical College Hospital
Beijing, , China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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rTMSPDFOG-PUMCH
Identifier Type: -
Identifier Source: org_study_id
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