Transcranial Direct Current Stimulation for Freezing of Gait

NCT ID: NCT02266004

Last Updated: 2020-06-30

Study Results

Results available

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

9 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-09-12

Study Completion Date

2018-06-27

Brief Summary

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This study will evaluate the effects of transcranial direct current stimulation (tDCS) in combination with locomotor training in patients with Parkinson's disease (PD) and freezing of gait (FOG).

Detailed Description

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Conditions

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Parkinson's Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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tDCS+ LT

Transcranial direct current stimulation(tDCS) plus locomotor training (LT) 3x per week for 3 consecutive weeks.

Group Type EXPERIMENTAL

Transcranial Direct Current Stimulation (tDCS)

Intervention Type DEVICE

Anodal tDCS will be applied for the duration of the walking training at 2 milliamps with IOMED Phoresor.

locomotor training

Intervention Type OTHER

An individualized dual-task walking program for approximately 30 minutes.

Interventions

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Transcranial Direct Current Stimulation (tDCS)

Anodal tDCS will be applied for the duration of the walking training at 2 milliamps with IOMED Phoresor.

Intervention Type DEVICE

locomotor training

An individualized dual-task walking program for approximately 30 minutes.

Intervention Type OTHER

Other Intervention Names

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tDCS

Eligibility Criteria

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Inclusion Criteria

1. age 18- 80
2. Parkinson's disease stages 2-3 Hoehn and Yahr.
3. Presence of Freezing of Gait
4. Stable medication regimen
5. Time to complete TUG \>12 seconds

Exclusion Criteria

1. medical condition that would interfere with walking and training for 30 minutes
2. unable to perform timed up and go in the off condition
3. history of seizures
4. implanted deep brain stimulator, pacemaker or any other electronic device.
5. dementia
6. Adults unable to consent, individuals who are not yet adults (infants, children, teenagers) pregnant women, prisoners will not be considered for participation
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Miami

OTHER

Sponsor Role lead

Responsible Party

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Corneliu C Luca

Assisstant Professor of Neurology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Corneliu Luca, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Miami

Locations

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University of Miami

Miami, Florida, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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20140127

Identifier Type: -

Identifier Source: org_study_id

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