Hydrogen-rich Water for Molecular and Phenotypic Biomarkers of Aging

NCT ID: NCT04430803

Last Updated: 2021-04-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-09-15

Study Completion Date

2021-04-01

Brief Summary

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This study evaluates the effects of six-month hydrogen-rich water intake on molecular and phenotypic biomarkers of aging in men and women aged 70 years and over.

Detailed Description

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Conditions

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Aging

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Hydrogen-rich water

Hydrogen-rich water (Rejuvenation, HRW Natural Health Products Inc.)

* 8 ppm of hydrogen
* Administered one dose two times per day on an empty stomach in the morning and at the evening

Group Type EXPERIMENTAL

Hydrogen-rich water

Intervention Type DIETARY_SUPPLEMENT

A tablet that produces hydrogen dissolved in a glass of water

Control water

Tap water

* 0 ppm of hydrogen
* Administered one dose two times per day on an empty stomach in the morning and at the evening

Group Type PLACEBO_COMPARATOR

Control Water

Intervention Type OTHER

A glass of tap water

Interventions

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Hydrogen-rich water

A tablet that produces hydrogen dissolved in a glass of water

Intervention Type DIETARY_SUPPLEMENT

Control Water

A glass of tap water

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age \> 70 years
* Free of acute disorders

Exclusion Criteria

* History of dietary supplement use during the past 4 weeks
Minimum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Novi Sad, Faculty of Sport and Physical Education

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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FSPE Applied Bioenergetics Lab

Novi Sad, Vojvodina, Serbia

Site Status

Countries

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Serbia

References

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Xia X, Chen W, McDermott J, Han JJ. Molecular and phenotypic biomarkers of aging. F1000Res. 2017 Jun 9;6:860. doi: 10.12688/f1000research.10692.1. eCollection 2017.

Reference Type BACKGROUND
PMID: 28663789 (View on PubMed)

Zanini D, Todorovic N, Korovljev D, Stajer V, Ostojic J, Purac J, Kojic D, Vukasinovic E, Djordjievski S, Sopic M, Guzonjic A, Ninic A, Erceg S, Ostojic SM. The effects of 6-month hydrogen-rich water intake on molecular and phenotypic biomarkers of aging in older adults aged 70 years and over: A randomized controlled pilot trial. Exp Gerontol. 2021 Nov;155:111574. doi: 10.1016/j.exger.2021.111574. Epub 2021 Oct 1.

Reference Type DERIVED
PMID: 34601077 (View on PubMed)

Other Identifiers

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281048E-HRW/2020

Identifier Type: -

Identifier Source: org_study_id

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