Magnetic Resonance Imaging to Detect Signs of Viral Pneumonia in Patients With Coronavirus Infection.

NCT ID: NCT04424355

Last Updated: 2023-03-21

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 25 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2020-05-19
• Study Completion Date: 2021-12-20

Brief Summary

Since the onset of the COVID-19 pandemic, the importance of chest computed tomography (CT) in detecting signs of viral pneumonia has become clear from the literature. However, the increased patient flow creates an additional pressure on CT centers. We believe, the use of chest magnetic resonance imaging (MRI) can help to test patients for CОVID-19 when CT scan is not available. Lung MRI may be useful in routing a patient in a difficult epidemiological situation.

Detailed Description

Currently, with increased load of CT studies, alternative methods of viral pneumonia signs' visualization are required.

Investigators hypothesize that chest MRI could be a test for detecting pulmonary features of COVID-19. They consider using MRI to assess COVID-19 viral pneumonia. Absence of radiation exposure to patients is a clear advantage of MRI.

This is a prospective, observational cohort study assessing patients with suspected COVID-19. It's primary goal is to determine the ability of multiparametric MRI to detect lung abnormalities - ground-glass opacity (GGO), consolidation, "crazy paving" pattern, pleuritis - in comparison to CT scan. In this study each patient with suspected pneumonia will sequentially undergo both chest CT and MRI during his/her visit. Scan protocols will be identical for each patient. Each participants completed an online questionnaire.

Conditions

Coronavirus Infections; Pneumonia

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: PROSPECTIVE

Study Groups

Patients with suspected pneumonia COVID-19

Chest MRI findings: bilateral, diffuse ground-glass opacity (GGO), consolidation, "crazy paving" pattern, pleuritis.

No interventions assigned to this group

Patients with suspected pneumonia with COVID -19

Chest CT findings: bilateral, diffuse ground-glass opacity (GGO), consolidation, "crazy paving" pattern, pleuritis.

Chest MRI

Intervention Type: DIAGNOSTIC_TEST

Patients referred by the primary care physician with suspected pneumonia

Interventions

Chest MRI

Patients referred by the primary care physician with suspected pneumonia

Intervention Type: DIAGNOSTIC_TEST

Other Intervention Names

Chest CT scan

Eligibility Criteria

Inclusion Criteria

• A referral from the attending physician for a chest CT scan
• Suspected pneumonia
• Signed informed consent
• Over 18 years old

Exclusion Criteria

• Pregnant or nursing women
• Presence of foreign implanted objects in the body at the scan level (including cardiac pacemakers, spine metalware)

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department

OTHER

Sponsor Role: lead

Responsible Party

Sergey Morozov

Chief Research Officer

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department

Moscow, , Russia

Countries

Russia

Other Identifiers

2020-2

Identifier Type: -

Identifier Source: org_study_id