Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
71 participants
OBSERVATIONAL
2016-04-30
2019-04-30
Brief Summary
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Detailed Description
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1. To determine if white matter hyperintensities on MRI scans of the brain are altered by aging and exercise training status.
2. To determine the interaction of aging and habitual physical activity on functional connectivity in the brain.
Conditions
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Keywords
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Exercise trained young adults
Exercise trained young adults between the age of 18-35 years.
MRI
Participants will undergo an MRI scan
Sedentary young adults
Sedentary young adults between the age of 18-35 years.
MRI
Participants will undergo an MRI scan
Exercise trained older adults
Exercise trained older adults between the age of 55-75 years.
MRI
Participants will undergo an MRI scan
Sedentary older adults
Sedentary older adults between the age of 55-75 years.
MRI
Participants will undergo an MRI scan
Interventions
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MRI
Participants will undergo an MRI scan
Eligibility Criteria
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Inclusion Criteria
* Body mass index \<34 kg/m2
* Physically active (exercise more than 3 times per week for at least 30 min) or sedentary (no formal exercise over 1 hour per week)
Exclusion Criteria
* History or evidence of: hepatic disease, renal disease, hematological disease, peripheral vascular disease, stroke/neurovascular disease, diabetes, hypertension
* Part of a vulnerable population (e.g. pregnant women, prisoner, individuals lacking capacity to consent, etc.)
18 Years
75 Years
ALL
Yes
Sponsors
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National Institutes of Health (NIH)
NIH
University of Wisconsin, Madison
OTHER
Responsible Party
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Principal Investigators
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Jill N Barnes, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Wisconsin, Madison
Locations
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Gymnasium-Natatorium
Madison, Wisconsin, United States
Countries
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References
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Other Identifiers
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CVR-AAA4385
Identifier Type: OTHER
Identifier Source: secondary_id
A176000
Identifier Type: OTHER
Identifier Source: secondary_id
EDUC/KINESIOLOGY/KINESIO
Identifier Type: OTHER
Identifier Source: secondary_id
2015-1611
Identifier Type: -
Identifier Source: org_study_id