Analysis of Breath Volatile Organic Compounds After Dyspnea Induced in the Healthy Subject.
NCT ID: NCT04418973
Last Updated: 2020-10-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
41 participants
INTERVENTIONAL
2020-09-07
2020-10-14
Brief Summary
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Called volatolom corresponds to the set of volatile organic compounds (VOCs) contained in exhaled air.
The analysis of volatolom can be done either by the methods based on mass spectrometry which allows the identification of each VOC in the exhaled air or by the use of electronic noses which are more simple to use, less specific and produce a quantitive signal change based on pattern recognition algorithms providing a global profile of the VOC without identifying them.
The aim of the study is to determine whether the analysis of VOCs in exhaled air would identify biomarkers related to the intensity and type of experimental dyspnea.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
OTHER
NONE
Study Groups
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A - load/apnea
Threshold inspiratory load then apnea
VOCs analysis in exhaled air
using an electronic nose and a mass spectrometry
B- apnea/load
apnea than threshold inspiratory load
VOCs analysis in exhaled air
using an electronic nose and a mass spectrometry
Interventions
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VOCs analysis in exhaled air
using an electronic nose and a mass spectrometry
Eligibility Criteria
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Inclusion Criteria
* no dyspnea
* non smoking or daily smoking more than 5 years packs
* perfect knowing of the French language
* the consent form signed
* affiliated to a health insurance plan
Exclusion Criteria
* history of asthma or Chronic obstructive pulmonary disease (COPD)
* personal or family atopy
* cannabis use
* electronic cigarette
* medication except contraception
* pregnant woman
* without liberty or guardianship
18 Years
ALL
Yes
Sponsors
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Hopital Foch
OTHER
Responsible Party
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Principal Investigators
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Philippe Devillier
Role: PRINCIPAL_INVESTIGATOR
Hopital Foch
Locations
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Foch hospital
Suresnes, , France
Countries
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Other Identifiers
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2019_0074
Identifier Type: -
Identifier Source: org_study_id
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