Brain TV (Tissue Velocimetry) for Emergency Assessment of Suspected Stroke

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

102 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-08-01

Study Completion Date

2023-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study uses a Doppler ultrasound technique being developed at the University of Leicester called \"Brain Tissue Velocimetry\" (Brain TV), to investigate brain tissue motion over the cardiac cycle.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Ischaemic Lesions in Acute Intracerebral Haemorrhage

NCT06410274

Intracerebral Haemorrhage

RECRUITING

The Relationship Between Controlling Risk Factors and Cerebral Haemodynamics in Lacunar Stroke

NCT06354881

Lacunar Stroke

RECRUITING

Third Ventricle Echographic Study for Neuro-intensive Care Unit Patients

NCT02830269

Neuro-intensive Care Unit Patients Brain Injuries

COMPLETED

Head Position on Cerebral Haemodynamics in Acute Ischemic Stroke and Controls

NCT02932540

Ischemic Stroke

COMPLETED

Emergency Stroke Unit for Acute Cerebrovascular Events: A Prospective, Single-arm Trial With a Historical Control Group

NCT06728592

Ischemic Stroke Intracerebral Hemorrhage Stroke +5 more

RECRUITING NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Brain motion is highly sensitive to heart and brain biomechanics, but the impact of brain injury on brain tissue motion has yet to be explored. Preliminary brain tissue motion measurements from a small number of patients suggest that brain biomechanics may be disturbed in the presence of brain injury. This study combines transcranial tissue Doppler (TCTD) ultrasound with brain magnetic resonance imaging (MRI) to establish whether analysis of brain tissue motion provides clinically useful information for emergency diagnosis and monitoring of suspected stroke.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Stroke

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Transcranial Tissue Doppler (TCTD)

Doppler ultrasound technique called "Brain Tissue Velocimetry" (Brain TV), to investigate brain tissue motion over the cardiac cycle.

Intervention Type DIAGNOSTIC_TEST

Brain Magnetic Resonance Imaging

Brain MRI for investigation of brain tissue motion in the presence of suspected stroke.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Participant (or consultee) is willing and able to give informed consent (or assent) for participation in the study.
* Adult, aged 18 years or over.
* Suspected stroke (any severity and any stroke type).

Exclusion Criteria

* Unable (in the investigators' opinion), or unwilling, to comply with the study requirements.
* Patients with pre-existing chronic brain conditions that may make affect informed consent, such as severe learning difficulties, dementia, or Alzheimer's disease, will be excluded.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No