Efficacy of Narrow Band Spectrum Endoscopy for the Diagnosis of Gastric Antral Vascular Ectasia in Patients With Liver Cirrhosis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-11-11

Study Completion Date

2021-03-01

Brief Summary

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the study aims to evaluate the role of similar technology of Narrow Band Imaging VIST video intelligent staining technology in the diagnosis of Gastric Antral Vascular ectasia in cirrhotic patients

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Detailed Description

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VIST (Video intelligent staining technology) is used to the diagnosis of GAVE as the form of ectatic vessels in the antrum in instead of erosions in the antrum by White light endoscopy which can mislead the diagnosis to Portal hypertension gastropathy. Targeted biopsies are taken and examined histopathologically in order to see if matching with VIST view. In addition, CD61 is used to highlight the diagnosis for more confirmation. CD61 is an immunohistochemistry platelets marker.

Conditions

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Gastric Antral Vascular Ectasia

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Interventions

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Upper gastrointestinal endoscopy and biopsy

Gastroscope with technology of VIST video intelligent staining technology for taking biopsies

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Patients with mucosal vascular lesions at the gastric antrum suspicious of GAVE of a linear striped form or a diffuse punctate form upon conventional WLE

Exclusion Criteria

* Connective tissue disorders like systemic sclerosis.
* Chronic kidney disease.
* Recent use of proton pump inhibitors in the last 14 days.
* History of gastric surgery or gastric cancer.
* Pernicious anemia.
* Recent history of non-steroidal anti-inflammatory drugs intake

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No