The Effects of Early Enteral Nutrition on Endoscopic Therapy of Esophagogastric Varices in Liver Cirrhosis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

397 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-01

Study Completion Date

2021-10-20

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study was to evaluate the safety of early enteral nutrition on endoscopic therapy of esophagogastric varices in Liver Cirrhosis ,and to assess the impact of different eating times on patients, so as to determine the best time for patients to obtain nutrition after surgery.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effect of Re-education on Rebleeding Rate After Endoscopic Treatment in Liver Cirrhosis

NCT05302661

Liver Cirrhosis Esophageal Varices Bleeding Gastric Variceal Bleeding +1 more

UNKNOWN NA

A Randomized Controlled Study on the Treatment of Cirrhosis Combined With Hypersplenism

NCT05055713

Liver Cirrhosis Esophageal and Gastric Varices Hypersplenism

UNKNOWN NA

Initiation of Diet in Esophageal Varices After Ligation (IDEAL) Study

NCT04890210

Liver Cirrhosis

UNKNOWN NA

Evaluation of Endoscopic Treatment Effect Based on HVPG

NCT06863519

Esophageal and Gastric Varices

ENROLLING_BY_INVITATION

Effects of Somatostatin on Post-endoscopic Portal Hemodynamic in Cirrhotic Patients With Esophageal Gastric Varices

NCT01426087

Esophageal Varices Secondary to Cirrhosis of Liver

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

For patients with gastroesophageal varices in Liver Cirrhosis,, there is no clear guideline and consensus on when to start eating after endoscopic treatment. In 2015, a randomized controlled study in Taiwan of China confirmed that compared with liquid diet given 48 h after endoscopic treatment, liquid diet given 4 h and started enteral nutrition would not increase the risk of rebleeding, and could improve the nutritional status of patients. However, some patients after endoscopic treatment would suffer from post-sternal pain, abdominal pain, nausea, vomiting and other discomforts, affecting appetite and delay the diet time. Based on the above research background, we observed and evaluated the safety and effectiveness of early enteral nutrition in patients with cirrhotic esophageal and gastric varices after endoscopic treatment, and analyzed the influencing factors of enteral nutrition in patients with cirrhotic esophageal and gastric varices after endoscopic treatment, so as to further clarify the optimal time for patients to eat after endoscopic treatment.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Liver Cirrhosis Esophageal and Gastric Varices

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

early enteral nutrition support group

Nutrient solution is provided through oral nutrient solution within 4-48 hours after endoscopic treatment

nutrient solution

Intervention Type DIETARY_SUPPLEMENT

For the patients with esophageal and gastric varices after endoscopic treatment，start taking the nutrient solution at the fourth hour.

parenteral Nutrition Group

Intravenous nutrition is provided within 48 hours after endoscopic treatment

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

nutrient solution

For the patients with esophageal and gastric varices after endoscopic treatment，start taking the nutrient solution at the fourth hour.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients with cirrhosis of gastroesophageal varices undergoing endoscopic therapy

Exclusion Criteria

* Endoscopic treatment of uncontrollable bleeding
* Accompanied with other endoscopic treatments that need to be fasting
* With obvious hepatic encephalopathy and liver failure
* Did not sign the informed consent form and refused to participate

Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No